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AK3 adenylate kinase 3 [ Bos taurus (domestic cattle) ]

Gene ID: 281613, updated on 4-Oct-2024

Summary

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Official Symbol
AK3provided by VGNC
Official Full Name
adenylate kinase 3provided by VGNC
Primary source
VGNC:VGNC:25772
See related
Ensembl:ENSBTAG00000017147
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
AK3L1
Orthologs
human mouse all
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Genomic context

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See AK3 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (39797153..39819493)

Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene RNA terminal phosphate cyclase like 1 Neighboring gene uncharacterized LOC132345947 Neighboring gene microRNA mir-101-2 Neighboring gene cell division cycle 37 like 1, HSP90 cochaperone Neighboring gene small EDRK-rich factor 2 pseudogene Neighboring gene spermatogenesis associated 6 like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The amino acid sequence of GTP:AMP phosphotransferase from beef-heart mitochondria. Extensive homology with cytosolic adenylate kinase. Wieland B, et al. Eur J Biochem, 1984 Sep 3. PMID 6088234
  2. The complete primary structure of GTP:AMP phosphotransferase from beef heart mitochondria. Tomasselli AG, et al. FEBS Lett, 1986 Jul 7. PMID 3013690
  3. Cloning and characterization of cDNA for mitochondrial GTP:AMP phosphotransferase of bovine liver. Yamada M, et al. J Biol Chem, 1989 Nov 15. PMID 2478555
  4. Three-dimensional structure of the complex between the mitochondrial matrix adenylate kinase and its substrate AMP. Diederichs K, et al. Biochemistry, 1990 Sep 4. PMID 2175649
  5. The refined structure of the complex between adenylate kinase from beef heart mitochondrial matrix and its substrate AMP at 1.85 A resolution. Diederichs K, et al. J Mol Biol, 1991 Feb 5. PMID 1994037

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC137322

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables adenylate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleobase-containing compound metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GTP:AMP phosphotransferase AK3, mitochondrial
Names
AK 3
GTP:AMP phosphotransferase, mitochondrial
adenylate kinase 3 alpha-like 1
adenylate kinase 3-like 1
NP_776662.1
XP_005210016.1
XP_024851216.1
XP_024851218.1
XP_059744933.1
XP_059744934.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174237.2 → NP_776662.1  GTP:AMP phosphotransferase AK3, mitochondrial

    See identical proteins and their annotated locations for NP_776662.1

    Status: PROVISIONAL

    Source sequence(s)
    M25757
    UniProtKB/Swiss-Prot
    P08760, Q29RI4
    Related
    ENSBTAP00000022789.3, ENSBTAT00000022789.5
    Conserved Domains (1) summary
    pfam00406
    Location:12 → 190
    ADK; Adenylate kinase

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    39797153..39819493
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059888951.1 → XP_059744934.1  GTP:AMP phosphotransferase AK3, mitochondrial isoform X2

  2. XM_005209959.5 → XP_005210016.1  GTP:AMP phosphotransferase AK3, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_005210016.1

    Conserved Domains (1) summary
    cl27057
    Location:1 → 120
    ADK; Adenylate kinase

  3. XM_024995450.2 → XP_024851218.1  GTP:AMP phosphotransferase AK3, mitochondrial isoform X2

    Conserved Domains (1) summary
    cl27057
    Location:1 → 120
    ADK; Adenylate kinase

  4. XM_059888950.1 → XP_059744933.1  GTP:AMP phosphotransferase AK3, mitochondrial isoform X1

  5. XM_024995448.2 → XP_024851216.1  GTP:AMP phosphotransferase AK3, mitochondrial isoform X2

    Conserved Domains (1) summary
    cl27057
    Location:1 → 120
    ADK; Adenylate kinase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P08760.3 GenPept UniProtKB/Swiss-Prot:P08760

Gene LinkOut

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