PRND prion like protein doppel [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: PRNDprovided by VGNC
Official Full Name: prion like protein doppelprovided by VGNC
Primary source: VGNC:VGNC:33355
See related: BGD:BT11735; Ensembl:ENSBTAG00000011010
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: dpl
Orthologs: human all
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Genomic context

Location:: chromosome: 13

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	13	NC_037340.1 (47086007..47091045)

Chromosome 13 - NC_037340.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Disparate Modes of Evolution Shaped Modern Prion (PRNP) and Prion-Related Doppel (PRND) Variation in Domestic Cattle
Title: Disparate Modes of Evolution Shaped Modern Prion (PRNP) and Prion-Related Doppel (PRND) Variation in Domestic Cattle.
Results showed that the region -323/+32 (+1 is the transcription start site) represents the promoter region and contains positive cis-acting elements
Title: Functional mapping of the bovine Doppel gene promoter region.
the genomic structure of three genes, PRNP, PRND, and RASSF2, within the syntenic region of the bovine genome is highly conserved in order and orientation.
Title: Comparative genomic organization of the human and bovine PRNP locus.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables copper ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular copper ion homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein homooligomerization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prion-like protein doppel

Names: prPLP; prion protein 2 (dublet)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.