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NPR3 natriuretic peptide receptor 3 [ Bos taurus (domestic cattle) ]

Gene ID: 281358, updated on 4-Oct-2024

Summary

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Gene symbol
NPR3
Gene description
natriuretic peptide receptor 3
See related
Ensembl:ENSBTAG00000007665
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See NPR3 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 20 NC_037347.1 (40915159..40995858, complement)

Chromosome 20 - NC_037347.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107131571 Neighboring gene microRNA mir-12058 Neighboring gene uncharacterized LOC104975283 Neighboring gene SUB1 regulator of transcription

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037347.1 Chromosome 20 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A variant form of the type C atrial natriuretic peptide receptor generated by alternative RNA splicing. Mizuno T, et al. J Biol Chem, 1993 Mar 5. PMID 8444892
  2. Mutational analysis of disulfide bridges in the type C atrial natriuretic peptide receptor. Itakura M, et al. J Biol Chem, 1994 Mar 18. PMID 8132555
  3. Atrial natriuretic peptide clearance receptor. Complete sequence and functional expression of cDNA clones. Fuller F, et al. J Biol Chem, 1988 Jul 5. PMID 2837487
  4. Purification and properties of active atrial-natriuretic-peptide receptor (type C) from bovine lung. Uchida K, et al. Biochem J, 1989 Nov 1. PMID 2557006, Free PMC Article
  5. Structure of the bovine atrial natriuretic peptide receptor (type C) gene. Saheki T, et al. J Biol Chem, 1991 Jun 15. PMID 1645726

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables natriuretic peptide receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide hormone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of blood pressure IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vasodilation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
atrial natriuretic peptide receptor 3
Names
ANP-C
ANPR-C
ANPRC
NPR-C
atrial natriuretic peptide C-type receptor
atrial natriuretic peptide clearance receptor
atrial natriuretic peptide receptor type C
atrionatriuretic peptide receptor C
natriuretic peptide receptor C
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174127.2 → NP_776552.1  atrial natriuretic peptide receptor 3 precursor

    See identical proteins and their annotated locations for NP_776552.1

    Status: PROVISIONAL

    Source sequence(s)
    J03876
    UniProtKB/Swiss-Prot
    P10730, P20644
    Related
    ENSBTAP00000069735.1, ENSBTAT00000074857.2
    Conserved Domains (3) summary
    cd06386
    Location:50 → 442
    PBP1_NPR_C_like; Ligand-binding domain of type C natriuretic peptide receptor
    cd12841
    Location:471 → 503
    TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
    pfam01094
    Location:67 → 420
    ANF_receptor; Receptor family ligand binding region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037347.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    40915159..40995858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024981201.2 → XP_024836969.1  atrial natriuretic peptide receptor 3 isoform X1

    UniProtKB/Swiss-Prot
    P10730, P20644
    Conserved Domains (2) summary
    cd06386
    Location:50 → 442
    PBP1_NPR_C_like; Ligand-binding domain of type C natriuretic peptide receptor
    cl25995
    Location:467 → 502
    TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P10730.2 GenPept UniProtKB/Swiss-Prot:P10730

Gene LinkOut

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Molecular Biology Databases
Research Materials