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VIT vitrin [ Bos taurus (domestic cattle) ]

Gene ID: 280957, updated on 4-Oct-2024

Summary

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Official Symbol
VITprovided by VGNC
Official Full Name
vitrinprovided by VGNC
Primary source
VGNC:VGNC:36802
See related
BGD:BT23370; Ensembl:ENSBTAG00000024980
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See VIT in Genome Data Viewer
Location:
chromosome: 11
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (19157463..19281023)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene cysteine rich transmembrane BMP regulator 1 Neighboring gene fasciculation and elongation protein zeta 2 Neighboring gene uncharacterized LOC112448870 Neighboring gene striatin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. VIT-1: the second member of a new branch of the von Willebrand factor A domain superfamily. Mayne R, et al. Biochem Soc Trans, 1999 Dec. PMID 10830112
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell-substrate adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in interstitial matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vitrin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173971.2 → NP_776396.1  vitrin precursor

    See identical proteins and their annotated locations for NP_776396.1

    Status: PROVISIONAL

    Source sequence(s)
    AF063832
    UniProtKB/Swiss-Prot
    Q95LI2
    UniProtKB/TrEMBL
    A0AAA9TIJ4
    Related
    ENSBTAP00000085659.1, ENSBTAT00000094226.1
    Conserved Domains (3) summary
    cd01472
    Location:468 → 628
    vWA_collagen; von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins. This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form ...
    pfam03815
    Location:44 → 133
    LCCL; LCCL domain
    cl00057
    Location:267 → 430
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    19157463..19281023
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010809893.4 → XP_010808195.1  vitrin isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MWW0, A0AAA9TIJ4
    Related
    ENSBTAP00000060091.1, ENSBTAT00000070602.2
    Conserved Domains (3) summary
    cd01472
    Location:442 → 602
    vWA_collagen; von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins. This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form ...
    pfam03815
    Location:44 → 133
    LCCL; LCCL domain
    cl00057
    Location:241 → 404
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95LI2.2 GenPept UniProtKB/Swiss-Prot:Q95LI2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials