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OTC ornithine transcarbamylase [ Bos taurus (domestic cattle) ]

Gene ID: 280887, updated on 4-Oct-2024

Summary

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Official Symbol
OTCprovided by VGNC
Official Full Name
ornithine transcarbamylaseprovided by VGNC
Primary source
VGNC:VGNC:32482
See related
BGD:BT12487; Ensembl:ENSBTAG00000001488
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See OTC in Genome Data Viewer
Location:
chromosome: X
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (104841977..104918525, complement)

Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene prostaglandin E synthase 3-like Neighboring gene ferritin light chain-like Neighboring gene retinitis pigmentosa GTPase regulator Neighboring gene sushi repeat containing protein X-linked Neighboring gene peptidyl-prolyl cis-trans isomerase D-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables amino acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ornithine carbamoyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in arginine biosynthetic process via ornithine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in citrulline biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ornithine transcarbamylase, mitochondrial
Names
OTCase
ornithine carbamoyltransferase, mitochondrial
NP_803453.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177487.2 → NP_803453.1  ornithine transcarbamylase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_803453.1

    Status: PROVISIONAL

    Source sequence(s)
    AF134841
    UniProtKB/Swiss-Prot
    Q9N1U7
    UniProtKB/TrEMBL
    A0AAA9U0N6
    Related
    ENSBTAP00000001947.3, ENSBTAT00000001947.4
    Conserved Domains (3) summary
    PRK00779
    Location:36 → 342
    PRK00779; ornithine carbamoyltransferase; Provisional
    pfam00185
    Location:188 → 341
    OTCace; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
    pfam02729
    Location:41 → 181
    OTCace_N; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    104841977..104918525 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9N1U7.1 GenPept UniProtKB/Swiss-Prot:Q9N1U7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials