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CPSF4 cleavage and polyadenylation specific factor 4 [ Bos taurus (domestic cattle) ]

Gene ID: 280875, updated on 4-Oct-2024

Summary

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Official Symbol
CPSF4provided by VGNC
Official Full Name
cleavage and polyadenylation specific factor 4provided by VGNC
Primary source
VGNC:VGNC:27673
See related
BGD:BT16046; Ensembl:ENSBTAG00000002090
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
NAR
Orthologs
human mouse all
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Genomic context

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See CPSF4 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (36959412..36971751, complement)

Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 892 Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene ATP synthase membrane subunit f Neighboring gene pentatricopeptide repeat domain 1 Neighboring gene BUD31 homolog Neighboring gene PDGFA associated protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. HPV-16 E2 contributes to induction of HPV-16 late gene expression by inhibiting early polyadenylation. Johansson C, et al. EMBO J, 2012 May 22. PMID 22617423, Free PMC Article
  2. The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins. Barabino SM, et al. Genes Dev, 1997 Jul 1. PMID 9224719
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of mRNA cleavage and polyadenylation specificity factor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cleavage and polyadenylation specificity factor subunit 4
Names
CPSF 30 kDa subunit
cleavage and polyadenylation specific factor 4, 30kDa
cleavage and polyadenylation specificity factor 30 kDa subunit
cleavage-polyadenylation specificity factor, 30 kD

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173942.2 → NP_776367.1  cleavage and polyadenylation specificity factor subunit 4

    See identical proteins and their annotated locations for NP_776367.1

    Status: PROVISIONAL

    Source sequence(s)
    U96448
    UniProtKB/Swiss-Prot
    O19137
    UniProtKB/TrEMBL
    A0AAA9SPB0
    Related
    ENSBTAP00000085756.1, ENSBTAT00000130305.1
    Conserved Domains (1) summary
    COG5084
    Location:25 → 176
    YTH1; Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    36959412..36971751 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005225003.4 → XP_005225060.1  cleavage and polyadenylation specificity factor subunit 4 isoform X1

    See identical proteins and their annotated locations for XP_005225060.1

    UniProtKB/TrEMBL
    A0AAA9TBD9, A0AAF6YJ37
    Related
    ENSBTAP00000002701.6, ENSBTAT00000002701.7
    Conserved Domains (1) summary
    COG5084
    Location:25 → 211
    YTH1; Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only]

  2. XM_005225004.4 → XP_005225061.1  cleavage and polyadenylation specificity factor subunit 4 isoform X2

    See identical proteins and their annotated locations for XP_005225061.1

    UniProtKB/TrEMBL
    A0AAA9SPB0
    Conserved Domains (1) summary
    COG5084
    Location:25 → 176
    YTH1; Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O19137.1 GenPept UniProtKB/Swiss-Prot:O19137

Gene LinkOut

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