CEL carboxyl ester lipase [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: CELprovided by VGNC
Official Full Name: carboxyl ester lipaseprovided by VGNC
Primary source: VGNC:VGNC:27165
See related: BGD:BT11946; Ensembl:ENSBTAG00000007486
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	11	NC_037338.1 (103058913..103067774)

Chromosome 11 - NC_037338.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

analysis of the structure-function relationships of rabbit liver esterase 1 and bovine pancreatic bile-salt-activated lipase
Title: Non-lipolytic and lipolytic sequence-related carboxylesterases: a comparative study of the structure-function relationships of rabbit liver esterase 1 and bovine pancreatic bile-salt-activated lipase.
Bovine cholesterol esterase increase the incorporation of micellar cholesterol into rat intestinal brush border membranes.
Title: Cholesterol esterase bound to intestinal brush border membranes does not accelerate incorporation of micellar cholesterol into absorptive cells.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables neurexin family protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables signaling receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables sterol ester esterase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables triacylglycerol lipase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chemical synaptic transmission	IEA Inferred from Electronic Annotation more info	PubMed
involved_in modulation of chemical synaptic transmission	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neuron cell-cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in postsynaptic membrane assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in presynaptic membrane assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in synaptic vesicle endocytosis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cell surface	IEA Inferred from Electronic Annotation more info	PubMed
located_in postsynaptic specialization membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in synapse	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: bile salt-activated lipase

Names: BAL; BSSL; bile salt-stimulated lipase; cholesterol esterase; pancreatic lysophospholipase; sterol esterase

NP_001013601.1

EC 3.1.1.13

EC 3.1.1.3

EC 3.1.1.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013583.1 → NP_001013601.1 bile salt-activated lipase precursor

See identical proteins and their annotated locations for NP_001013601.1

Status: PROVISIONAL

Source sequence(s)

BT021633

UniProtKB/TrEMBL

A6QQ45, Q58DG4

Related

ENSBTAP00000032584.3, ENSBTAT00000032655.4

Conserved Domains (2) summary

COG0657
Location:118 → 351

Aes; Acetyl esterase/lipase [Lipid transport and metabolism]

pfam00135
Location:24 → 542

COesterase; Carboxylesterase family