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AMT aminomethyltransferase [ Bos taurus (domestic cattle) ]

Gene ID: 280719, updated on 4-Oct-2024

Summary

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Gene symbol
AMT
Gene description
aminomethyltransferase
See related
BGD:BT25031; Ensembl:ENSBTAG00000002321
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See AMT in Genome Data Viewer
Location:
chromosome: 22
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (50693282..50697608)

Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene NEDD8-conjugating enzyme UBE2F-like Neighboring gene nicolin 1, tubulin polyglutamylase complex subunit Neighboring gene T cell leukemia translocation altered Neighboring gene ras homolog family member A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. cDNA sequence, in vitro synthesis, and intramitochondrial lipoylation of H-protein of the glycine cleavage system. Fujiwara K, et al. J Biol Chem, 1990 Oct 15. PMID 2211640
  2. Isolation and sequence determination of cDNA encoding T-protein of the glycine cleavage system. Okamura-Ikeda K, et al. J Biol Chem, 1991 Mar 15. PMID 2002038
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aminomethyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
aminomethyltransferase, mitochondrial
Names
GCVT
aminomethyltransferase (glycine cleavage system protein T)
glycine cleavage system T protein
NP_803451.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177485.2 → NP_803451.1  aminomethyltransferase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_803451.1

    Status: PROVISIONAL

    Source sequence(s)
    M59799
    UniProtKB/Swiss-Prot
    P25285
    UniProtKB/TrEMBL
    A0AAA9TRT8
    Related
    ENSBTAP00000100030.1, ENSBTAT00000131061.1
    Conserved Domains (3) summary
    PLN02319
    Location:3 → 394
    PLN02319; aminomethyltransferase
    pfam01571
    Location:33 → 285
    GCV_T; Aminomethyltransferase folate-binding domain
    pfam08669
    Location:295 → 386
    GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    50693282..50697608
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25285.1 GenPept UniProtKB/Swiss-Prot:P25285

Gene LinkOut

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