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TF transferrin [ Bos taurus (domestic cattle) ]

Gene ID: 280705, updated on 18-Aug-2024

Summary

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Gene symbol
TF
Gene description
transferrin
See related
BGD:BT10778; Ensembl:ENSBTAG00000007273
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (135579069..135618070, complement)

Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene KAT8 regulatory NSL complex subunit 2-like Neighboring gene solute carrier organic anion transporter family member 2A1 Neighboring gene RAB6B, member RAS oncogene family Neighboring gene transfer RNA arginine (anticodon ACG) Neighboring gene inhibitor of carbonic anhydrase Neighboring gene DNA topoisomerase II binding protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transferrin Binding Protein B and Transferrin Binding Protein A2 Expand the Transferrin Recognition Range of Histophilus somni. Pogoutse AK, et al. J Bacteriol, 2020 Jun 25. PMID 32366593, Free PMC Article
  2. Production and characterization of chimeric transferrins for the determination of the binding domains for bacterial transferrin receptors. Retzer MD, et al. J Biol Chem, 1996 Jan 12. PMID 8557646
  3. A single nucleotide polymorphism in the coding region of bovine transferrin is associated with milk fat yield. Sanz A, et al. Genet Mol Res, 2010 May 4. PMID 20449817

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Transferrin Binding Protein B and Transferrin Binding Protein A2 Expand the Transferrin Recognition Range of Histophilus somni.
    Title: Transferrin Binding Protein B and Transferrin Binding Protein A2 Expand the Transferrin Recognition Range of Histophilus somni.
  2. The TF gene has an effect on milk fat yield.
    Title: A single nucleotide polymorphism in the coding region of bovine transferrin is associated with milk fat yield.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC139350

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ferric iron binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in antibacterial humoral response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular iron ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in early endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in recycling endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serotransferrin
Names
beta-1 metal-binding globulin
siderophilin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177484.3 → NP_803450.2  serotransferrin precursor

    See identical proteins and their annotated locations for NP_803450.2

    Status: PROVISIONAL

    Source sequence(s)
    BC122602
    UniProtKB/Swiss-Prot
    Q0IIK2, Q29443
    UniProtKB/TrEMBL
    G3X6N3
    Related
    ENSBTAP00000009564.6, ENSBTAT00000009564.6
    Conserved Domains (4) summary
    smart00094
    Location:364 → 689
    TR_FER; Transferrin
    cd13617
    Location:364 → 688
    PBP2_transferrin_C; The C-lobe of transferrin, a member of the type 2 periplasmic binding protein fold superfamily
    cd13618
    Location:24 → 350
    PBP2_transferrin_N; The N-lobe of transferrin, a member of the type 2 periplasmic binding protein fold superfamily
    pfam00405
    Location:25 → 351
    Transferrin; Transferrin

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    135579069..135618070 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q29443.1 GenPept UniProtKB/Swiss-Prot:Q29443

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials