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Arsj arylsulfatase J [ Mus musculus (house mouse) ]

Gene ID: 271970, updated on 18-Sep-2024

Summary

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Official Symbol
Arsjprovided by MGI
Official Full Name
arylsulfatase Jprovided by MGI
Primary source
MGI:MGI:2443513
See related
Ensembl:ENSMUSG00000046561 AllianceGenome:MGI:2443513
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D830047F08; 9330196J05Rik
Summary
Predicted to enable metal ion binding activity and sulfuric ester hydrolase activity. Predicted to be located in actin cytoskeleton. Is expressed in Meckel's cartilage; elbow joint primordium; otic capsule; and vertebral cartilage condensation. Orthologous to human ARSJ (arylsulfatase family member J). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in limb E14.5 (RPKM 1.9), bladder adult (RPKM 1.7) and 15 other tissues See more
Orthologs
human all
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Genomic context

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See Arsj in Genome Data Viewer
Location:
3 G1; 3 55.97 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (126157566..126234025)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (126363852..126440374)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40146 Neighboring gene STARR-seq mESC enhancer starr_08928 Neighboring gene STARR-seq mESC enhancer starr_08929 Neighboring gene family with sequence similarity 98, member B pseudogene Neighboring gene STARR-seq mESC enhancer starr_08930 Neighboring gene predicted gene, 35408 Neighboring gene STARR-seq mESC enhancer starr_08931 Neighboring gene STARR-seq mESC enhancer starr_08932 Neighboring gene STARR-seq mESC enhancer starr_08933 Neighboring gene 40S ribosomal protein S28 pseudogene Neighboring gene predicted gene, 46823 Neighboring gene STARR-seq mESC enhancer starr_08934 Neighboring gene STARR-seq mESC enhancer starr_08935

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Expression patterns of sulfatase genes in the developing mouse embryo. Ratzka A, et al. Dev Dyn, 2010 Jun. PMID 20503373
  2. Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship. Sardiello M, et al. Hum Mol Genet, 2005 Nov 1. PMID 16174644
  3. Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development. Uijtdewilligen PJE, et al. Biomed Res Int, 2018. PMID 30228991, Free PMC Article
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sulfuric ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
arylsulfatase J
Names
ASJ
NP_775627.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173451.4 → NP_775627.1  arylsulfatase J precursor

    See identical proteins and their annotated locations for NP_775627.1

    Status: VALIDATED

    Source sequence(s)
    AC091322, AC114551
    Consensus CDS
    CCDS17822.1
    UniProtKB/Swiss-Prot
    Q8BKG5, Q8BL46, Q8BM89
    UniProtKB/TrEMBL
    Q32KI8, Q8BM79
    Related
    ENSMUSP00000091511.3, ENSMUST00000093976.4
    Conserved Domains (3) summary
    COG3119
    Location:71 → 507
    AslA; Arylsulfatase A or related enzyme [Inorganic ion transport and metabolism]
    cd16029
    Location:74 → 507
    4-S; N-acetylgalactosamine 4-sulfatase, also called arylsulftase B
    cl20644
    Location:493 → 531
    DUF4976; Domain of unknown function (DUF4976)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    126157566..126234025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BM89.1 GenPept UniProtKB/Swiss-Prot:Q8BM89

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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