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Nat14 N-acetyltransferase 14 [ Mus musculus (house mouse) ]

Gene ID: 269854, updated on 2-Nov-2024

Summary

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Official Symbol
Nat14provided by MGI
Official Full Name
N-acetyltransferase 14provided by MGI
Primary source
MGI:MGI:3039561
See related
Ensembl:ENSMUSG00000035285 AllianceGenome:MGI:3039561
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable N-acetyltransferase activity. Predicted to be located in membrane. Orthologous to human NAT14 (N-acetyltransferase 14 (putative)). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in frontal lobe adult (RPKM 13.5), cortex adult (RPKM 11.9) and 23 other tissues See more
Orthologs
human all
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Genomic context

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See Nat14 in Genome Data Viewer
Location:
7 A1; 7 2.85 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (4925250..4928005)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (4918877..4925006)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene 3-phosphoglycerate dehydrogenase pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E10424 Neighboring gene zinc finger protein 628 Neighboring gene microRNA 12202 Neighboring gene scavenger receptor cysteine rich family, 5 domains Neighboring gene STARR-positive B cell enhancer ABC_E6508 Neighboring gene SH3-binding domain kinase family, member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia. Wiame E, et al. Biochem J, 2009 Dec 14. PMID 19807691
  2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Results indicated that NAT8L, but not NAT14, catalysed the synthesis of NAA from L-aspartate and acetyl-CoA.
    Title: Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC57098

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables N-acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
probable N-acetyltransferase 14
NP_001345810.1
NP_001345811.1
NP_001345812.1
NP_001345813.1
NP_958743.1
XP_006540084.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001358881.1 → NP_001345810.1  probable N-acetyltransferase 14

    Status: VALIDATED

    Source sequence(s)
    AC157563
    Consensus CDS
    CCDS20749.1
    UniProtKB/Swiss-Prot
    Q8BVG8

  2. NM_001358882.1 → NP_001345811.1  probable N-acetyltransferase 14

    Status: VALIDATED

    Source sequence(s)
    AC157563
    Consensus CDS
    CCDS20749.1
    UniProtKB/Swiss-Prot
    Q8BVG8
    Related
    ENSMUSP00000147229.2, ENSMUST00000207687.2

  3. NM_001358883.1 → NP_001345812.1  probable N-acetyltransferase 14

    Status: VALIDATED

    Source sequence(s)
    AC157563
    Consensus CDS
    CCDS20749.1
    UniProtKB/Swiss-Prot
    Q8BVG8

  4. NM_001358884.1 → NP_001345813.1  probable N-acetyltransferase 14

    Status: VALIDATED

    Source sequence(s)
    AC157563
    Consensus CDS
    CCDS20749.1
    UniProtKB/Swiss-Prot
    Q8BVG8

  5. NM_201355.3 → NP_958743.1  probable N-acetyltransferase 14

    See identical proteins and their annotated locations for NP_958743.1

    Status: VALIDATED

    Source sequence(s)
    AK158627
    Consensus CDS
    CCDS20749.1
    UniProtKB/Swiss-Prot
    Q8BVG8
    Related
    ENSMUSP00000045354.6, ENSMUST00000047309.6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    4925250..4928005
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006540021.1 → XP_006540084.1  probable N-acetyltransferase 14 isoform X1

    See identical proteins and their annotated locations for XP_006540084.1

    UniProtKB/Swiss-Prot
    Q8BVG8
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BVG8.1 GenPept UniProtKB/Swiss-Prot:Q8BVG8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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