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Zscan20 zinc finger and SCAN domains 20 [ Mus musculus (house mouse) ]

Gene ID: 269585, updated on 17-Aug-2024

Summary

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Official Symbol
Zscan20provided by MGI
Official Full Name
zinc finger and SCAN domains 20provided by MGI
Primary source
MGI:MGI:2679268
See related
Ensembl:ENSMUSG00000061894 AllianceGenome:MGI:2679268
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfp31; Zkscan20; C130001F22
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including cerebral cortex; early conceptus; ganglia; genitourinary system; and lung. Orthologous to human ZSCAN20 (zinc finger and SCAN domain containing 20). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 1.4), thymus adult (RPKM 1.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Zscan20 in Genome Data Viewer
Location:
4 D2.2; 4 62.04 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (128472142..128503933, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (128578670..128610153, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene CUB and Sushi multiple domains 2 Neighboring gene high-mobility group box 4, opposite strand Neighboring gene STARR-seq mESC enhancer starr_11453 Neighboring gene predicted gene, 33656 Neighboring gene STARR-positive B cell enhancer ABC_E839 Neighboring gene STARR-seq mESC enhancer starr_11454 Neighboring gene predicted gene 12958 Neighboring gene toll-like receptor 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC30798

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger and SCAN domain-containing protein 20
Names
zinc finger protein 31
zinc finger with KRAB and SCAN domains 20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177758.5 → NP_808426.2  zinc finger and SCAN domain-containing protein 20

    See identical proteins and their annotated locations for NP_808426.2

    Status: VALIDATED

    Source sequence(s)
    AL611969
    Consensus CDS
    CCDS18672.2
    UniProtKB/Swiss-Prot
    B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
    Related
    ENSMUSP00000095487.3, ENSMUST00000097877.9
    Conserved Domains (4) summary
    COG5048
    Location:686 → 1020
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:948 → 968
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:41 → 126
    SCAN; SCAN domain
    pfam13837
    Location:476 → 561
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    128472142..128503933 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011240544.4 → XP_011238846.1  zinc finger and SCAN domain-containing protein 20 isoform X2

    Conserved Domains (4) summary
    COG5048
    Location:685 → 1019
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:947 → 967
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:41 → 126
    SCAN; SCAN domain
    pfam13837
    Location:315 → 396
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

  2. XM_036164141.1 → XP_036020034.1  zinc finger and SCAN domain-containing protein 20 isoform X6

    Conserved Domains (3) summary
    COG5048
    Location:256 → 590
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:518 → 538
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13837
    Location:46 → 127
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

  3. XM_036164140.1 → XP_036020033.1  zinc finger and SCAN domain-containing protein 20 isoform X2

    Conserved Domains (4) summary
    COG5048
    Location:685 → 1019
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:947 → 967
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:41 → 126
    SCAN; SCAN domain
    pfam13837
    Location:315 → 396
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

  4. XM_011240545.4 → XP_011238847.1  zinc finger and SCAN domain-containing protein 20 isoform X3

    Conserved Domains (4) summary
    COG5048
    Location:657 → 991
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:919 → 939
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13837
    Location:447 → 532
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
    cl02605
    Location:29 → 104
    SCAN; SCAN oligomerization domain

  5. XM_011240542.4 → XP_011238844.1  zinc finger and SCAN domain-containing protein 20 isoform X1

    See identical proteins and their annotated locations for XP_011238844.1

    UniProtKB/Swiss-Prot
    B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
    Conserved Domains (4) summary
    COG5048
    Location:686 → 1020
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:948 → 968
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:41 → 126
    SCAN; SCAN domain
    pfam13837
    Location:476 → 561
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

  6. XM_011240543.4 → XP_011238845.1  zinc finger and SCAN domain-containing protein 20 isoform X1

    See identical proteins and their annotated locations for XP_011238845.1

    UniProtKB/Swiss-Prot
    B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
    Conserved Domains (4) summary
    COG5048
    Location:686 → 1020
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:948 → 968
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:41 → 126
    SCAN; SCAN domain
    pfam13837
    Location:476 → 561
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

  7. XM_011240546.4 → XP_011238848.1  zinc finger and SCAN domain-containing protein 20 isoform X4

    See identical proteins and their annotated locations for XP_011238848.1

    Conserved Domains (3) summary
    COG5048
    Location:505 → 839
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:767 → 787
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13837
    Location:295 → 380
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

  8. XM_011240547.4 → XP_011238849.1  zinc finger and SCAN domain-containing protein 20 isoform X5

    See identical proteins and their annotated locations for XP_011238849.1

    UniProtKB/Swiss-Prot
    B2KFW1
    Conserved Domains (3) summary
    COG5048
    Location:257 → 591
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:519 → 539
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13837
    Location:47 → 132
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

  9. XM_006503133.4 → XP_006503196.1  zinc finger and SCAN domain-containing protein 20 isoform X1

    See identical proteins and their annotated locations for XP_006503196.1

    UniProtKB/Swiss-Prot
    B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
    Conserved Domains (4) summary
    COG5048
    Location:686 → 1020
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:948 → 968
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:41 → 126
    SCAN; SCAN domain
    pfam13837
    Location:476 → 561
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

  10. XM_006503131.3 → XP_006503194.1  zinc finger and SCAN domain-containing protein 20 isoform X1

    See identical proteins and their annotated locations for XP_006503194.1

    UniProtKB/Swiss-Prot
    B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
    Conserved Domains (4) summary
    COG5048
    Location:686 → 1020
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:948 → 968
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:41 → 126
    SCAN; SCAN domain
    pfam13837
    Location:476 → 561
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

  11. XM_006503134.4 → XP_006503197.1  zinc finger and SCAN domain-containing protein 20 isoform X1

    See identical proteins and their annotated locations for XP_006503197.1

    UniProtKB/Swiss-Prot
    B1AS93, B2KFW1, Q3UNF0, Q6DFW6, Q8BJ07
    Conserved Domains (4) summary
    COG5048
    Location:686 → 1020
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:948 → 968
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:41 → 126
    SCAN; SCAN domain
    pfam13837
    Location:476 → 561
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B2KFW1.2 GenPept UniProtKB/Swiss-Prot:B2KFW1

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