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Ms4a5 membrane-spanning 4-domains, subfamily A, member 5 [ Mus musculus (house mouse) ]

Gene ID: 269063, updated on 28-Oct-2024

Summary

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Official Symbol
Ms4a5provided by MGI
Official Full Name
membrane-spanning 4-domains, subfamily A, member 5provided by MGI
Primary source
MGI:MGI:2670985
See related
Ensembl:ENSMUSG00000054523 AllianceGenome:MGI:2670985
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be involved in cell surface receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human MS4A5 (membrane spanning 4-domains A5). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Restricted expression toward testis adult (RPKM 50.1) See more
Orthologs
human all
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Genomic context

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See Ms4a5 in Genome Data Viewer
Location:
19 A; 19 8.27 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (11251514..11261259, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (11273866..11283895, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930526L06 gene Neighboring gene STARR-seq mESC enhancer starr_45567 Neighboring gene membrane-spanning 4-domains, subfamily A, member 12 Neighboring gene STARR-positive B cell enhancer ABC_E11022 Neighboring gene membrane-spanning 4-domains, subfamily A, member 1 Neighboring gene STARR-positive B cell enhancer ABC_E3243 Neighboring gene STARR-seq mESC enhancer starr_45568 Neighboring gene STARR-seq mESC enhancer starr_45570 Neighboring gene membrane-spanning 4-domains, subfamily A, member 14 Neighboring gene membrane-spanning 4-domains, subfamily A, member 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Gene trapped (1) 
  • Targeted (1) 

General gene information

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Homology

Clone Names

  • MGC58438

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
membrane-spanning 4-domains subfamily A member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418543.1 → NP_001405472.1  membrane-spanning 4-domains subfamily A member 5 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC134839
    UniProtKB/TrEMBL
    Q2TVW9
    Related
    ENSMUSP00000139805.2, ENSMUST00000186937.7

  2. NM_183190.3 → NP_899013.1  membrane-spanning 4-domains subfamily A member 5 isoform 1

    See identical proteins and their annotated locations for NP_899013.1

    Status: VALIDATED

    Source sequence(s)
    AC134839
    Consensus CDS
    CCDS29596.1
    UniProtKB/TrEMBL
    Q810P8
    Related
    ENSMUSP00000066960.7, ENSMUST00000067673.13
    Conserved Domains (1) summary
    pfam04103
    Location:49 → 189
    CD20; CD20-like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    11251514..11261259 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527124.4 → XP_006527187.1  membrane-spanning 4-domains subfamily A member 5 isoform X1

    Conserved Domains (1) summary
    pfam04103
    Location:49 → 147
    CD20; CD20-like family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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