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plagl2 pleiomorphic adenoma gene-like 2 [ Danio rerio (zebrafish) ]

Gene ID: 259255, updated on 12-Sep-2024

Summary

Official Symbol
plagl2provided by ZNC
Official Full Name
pleiomorphic adenoma gene-like 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-020806-1
See related
Ensembl:ENSDARG00000076657 AllianceGenome:ZFIN:ZDB-GENE-020806-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in several structures, including axial vasculature; immature eye; lateral plate mesoderm; nervous system; and otic vesicle. Orthologous to human PLAGL2 (PLAG1 like zinc finger 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See plagl2 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (7590709..7674851, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (7653870..7741139, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene HCK proto-oncogene, Src family tyrosine kinase Neighboring gene transmembrane 9 superfamily protein member 4 Neighboring gene protein O-fucosyltransferase 1 Neighboring gene kinesin family member 3B

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein PLAGL2
Names
pleiomorphic adenoma protein-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153652.2NP_705938.1  zinc finger protein PLAGL2

    See identical proteins and their annotated locations for NP_705938.1

    Status: PROVISIONAL

    Source sequence(s)
    AF186476
    UniProtKB/TrEMBL
    Q9DG49
    Related
    ENSDARP00000104090.2, ENSDART00000115298.3
    Conserved Domains (2) summary
    sd00017
    Location:5676
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:99123
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    7590709..7674851 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005174102.5XP_005174159.1  zinc finger protein PLAGL2 isoform X1

    See identical proteins and their annotated locations for XP_005174159.1

    UniProtKB/TrEMBL
    A0A8M2BLD3, B3DK35
    Related
    ENSDARP00000147853.1, ENSDART00000185612.1
    Conserved Domains (2) summary
    sd00017
    Location:5676
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:99123
    zf-H2C2_2; Zinc-finger double domain