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Rwdd1 RWD domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 259218, updated on 2-Nov-2024

Summary

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Official Symbol
Rwdd1provided by RGD
Official Full Name
RWD domain containing 1provided by RGD
Primary source
RGD:631337
See related
EnsemblRapid:ENSRNOG00000042916 AllianceGenome:RGD:631337
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
sarip
Summary
Predicted to be involved in several processes, including androgen receptor signaling pathway; cellular response to testosterone stimulus; and positive regulation of androgen receptor activity. Predicted to be located in cytoplasm. Orthologous to human RWDD1 (RWD domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Muscle (RPKM 134.5), Heart (RPKM 104.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Rwdd1 in Genome Data Viewer
Location:
20q11
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (26493664..26510282, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (25949723..25967147, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (27534361..27552225, complement)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100910945 Neighboring gene uncharacterized LOC120098821 Neighboring gene tet methylcytosine dioxygenase 1 Neighboring gene trafficking protein particle complex subunit 3L Neighboring gene calcium homeostasis modulator family member 4 Neighboring gene calcium homeostasis modulator family member 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification and characterization of a novel thymus aging related protein Rwdd1. Kang N, et al. Cell Mol Immunol, 2008 Aug. PMID 18761815, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in androgen receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in cellular response to oxidative stress ISO
Inferred from Sequence Orthology
more info
  
involved_in cellular response to testosterone stimulus ISO
Inferred from Sequence Orthology
more info
  
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of androgen receptor activity IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of androgen receptor activity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
RWD domain-containing protein 1
Names
small androgen receptor-interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_147146.2 → NP_671487.1  RWD domain-containing protein 1

    See identical proteins and their annotated locations for NP_671487.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ132390
    UniProtKB/Swiss-Prot
    Q99ND9
    UniProtKB/TrEMBL
    A0A8I6ACH0, A6K3S3
    Related
    ENSRNOP00000062656.4, ENSRNOT00000068777.5
    Conserved Domains (2) summary
    pfam05773
    Location:6 → 111
    RWD; RWD domain
    pfam16543
    Location:144 → 197
    DFRP_C; DRG Family Regulatory Proteins, Tma46

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    26493664..26510282 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008772869.4 → XP_008771091.1  RWD domain-containing protein 1 isoform X1

    Conserved Domains (1) summary
    pfam16543
    Location:48 → 101
    DFRP_C; DRG Family Regulatory Proteins, Tma46
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99ND9.1 GenPept UniProtKB/Swiss-Prot:Q99ND9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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