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Or8b12b olfactory receptor family 8 subfamily B member 12B [ Mus musculus (house mouse) ]

Gene ID: 258744, updated on 2-Nov-2024

Summary

Official Symbol
Or8b12bprovided by MGI
Official Full Name
olfactory receptor family 8 subfamily B member 12Bprovided by MGI
Primary source
MGI:MGI:3030709
See related
Ensembl:ENSMUSG00000058628 AllianceGenome:MGI:3030709
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Olfr875; MOR161-4
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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Genomic context

See Or8b12b in Genome Data Viewer
Location:
9 A4; 9 20.8 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (37683933..37684936)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (37772637..37773640)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 8 subfamily A member 1 Neighboring gene STARR-seq mESC enhancer starr_23817 Neighboring gene olfactory receptor family 8 subfamily B member 12 Neighboring gene STARR-seq mESC enhancer starr_23819 Neighboring gene olfactory receptor family 8 subfamily B member 12C Neighboring gene predicted gene, 24764

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
PubMed 
involved_in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 875
Names
GA_x6K02T2PVTD-31458511-31459443
olfactory receptor MOR161-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146749.2NP_666960.2  olfactory receptor 875

    See identical proteins and their annotated locations for NP_666960.2

    Status: VALIDATED

    Source sequence(s)
    CT030124
    Consensus CDS
    CCDS22987.1
    UniProtKB/TrEMBL
    Q7TRE5, Q8VG17
    Related
    ENSMUSP00000079467.4, ENSMUST00000080634.4
    Conserved Domains (2) summary
    pfam00001
    Location:40289
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:30304
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    37683933..37684936
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)