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Or4d6 olfactory receptor family 4 subfamily D member 6 [ Mus musculus (house mouse) ]

Gene ID: 258673, updated on 11-Apr-2024

Summary

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Official Symbol
Or4d6provided by MGI
Official Full Name
olfactory receptor family 4 subfamily D member 6provided by MGI
Primary source
MGI:MGI:3031262
See related
Ensembl:ENSMUSG00000067524 AllianceGenome:MGI:3031262
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MOR239-5; Olfr1428
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
human all
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Genomic context

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See Or4d6 in Genome Data Viewer
Location:
19 A; 19 8.61 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (12085964..12093192, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (12108600..12115828, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily D member 10C Neighboring gene olfactory receptor family 4 subfamily Z member 4 Neighboring gene olfactory receptor family 5 subfamily A member 1 Neighboring gene olfactory receptor family 5 subfamily BB member 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  2. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  3. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
  4. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article
  5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC140907

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within detection of chemical stimulus involved in sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor family 4 subfamily D member 6
Names
GA_x6K02T2RE5P-2468394-2467450
olfactory receptor 1428
olfactory receptor MOR239-5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146678.2 → NP_666889.2  olfactory receptor family 4 subfamily D member 6

    See identical proteins and their annotated locations for NP_666889.2

    Status: PROVISIONAL

    Source sequence(s)
    BC119441
    Consensus CDS
    CCDS29622.1
    UniProtKB/TrEMBL
    Q0VDY1, Q7TQS0
    Related
    ENSMUSP00000085126.2, ENSMUST00000087824.2
    Conserved Domains (1) summary
    cd15936
    Location:35 → 291
    7tmA_OR4D-like; olfactory receptor 4D and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    12085964..12093192 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527103.3 → XP_006527166.1  olfactory receptor family 4 subfamily D member 6 isoform X1

    See identical proteins and their annotated locations for XP_006527166.1

    UniProtKB/TrEMBL
    Q0VDY1, Q7TQS0
    Related
    ENSMUSP00000150097.2, ENSMUST00000214103.2
    Conserved Domains (1) summary
    cd15936
    Location:35 → 291
    7tmA_OR4D-like; olfactory receptor 4D and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version

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