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Or2y1g olfactory receptor family 2 subfamily Y member 1G [ Mus musculus (house mouse) ]

Gene ID: 258463, updated on 2-Nov-2024

Summary

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Official Symbol
Or2y1gprovided by MGI
Official Full Name
olfactory receptor family 2 subfamily Y member 1Gprovided by MGI
Primary source
MGI:MGI:3031227
See related
Ensembl:ENSMUSG00000059864 AllianceGenome:MGI:3031227
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Olfr1393; MOR256-24
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Or2y1g in Genome Data Viewer
Location:
11 B1.2; 11 29.31 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (49154700..49183186)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (49263873..49292359)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6976 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:49057557-49057744 Neighboring gene predicted gene, 51893 Neighboring gene STARR-positive B cell enhancer ABC_E195 Neighboring gene mannoside acetylglucosaminyltransferase 1 Neighboring gene STARR-positive B cell enhancer ABC_E8994 Neighboring gene STARR-seq mESC enhancer starr_29373 Neighboring gene olfactory receptor family 2 subfamily Y member 1F Neighboring gene STARR-seq mESC enhancer starr_29374 Neighboring gene olfactory receptor family 2 subfamily Y member 1B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a type 1 diabetic mouse model. Schiazza AR, et al. Physiol Rep, 2021 Dec. PMID 34877823, Free PMC Article
  2. Renal olfactory receptor 1393 contributes to the progression of type 2 diabetes in a diet-induced obesity model. Shepard BD, et al. Am J Physiol Renal Physiol, 2019 Feb 1. PMID 30484350, Free PMC Article
  3. A Renal Olfactory Receptor Aids in Kidney Glucose Handling. Shepard BD, et al. Sci Rep, 2016 Oct 14. PMID 27739476, Free PMC Article
  4. Odorant and vomeronasal receptor genes in two mouse genome assemblies. Zhang X, et al. Genomics, 2004 May. PMID 15081110
  5. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a type 1 diabetic mouse model.
    Title: Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a type 1 diabetic mouse model.
  2. Renal Olfr1393 can contribute to the progression of type 2 diabetes, likely as a regulator of Na(+)-glucose cotransport in the proximal tubule.
    Title: Renal olfactory receptor 1393 contributes to the progression of type 2 diabetes in a diet-induced obesity model.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Clone Names

  • MGC123557, MGC123558

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor family 2 subfamily Y member 1G
Names
GA_x6K02T2QP88-6154577-6153642
MOR256-67_i
olfactory receptor 1393
olfactory receptor MOR256-24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146471.1 → NP_666682.1  olfactory receptor family 2 subfamily Y member 1G

    See identical proteins and their annotated locations for NP_666682.1

    Status: PROVISIONAL

    Source sequence(s)
    AY073627
    Consensus CDS
    CCDS24603.1
    UniProtKB/TrEMBL
    Q8VFA7
    Related
    ENSMUSP00000077962.2, ENSMUST00000078932.2
    Conserved Domains (2) summary
    pfam00001
    Location:41 → 289
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:35 → 304
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    49154700..49183186
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030246013.1 → XP_030101873.1  olfactory receptor family 2 subfamily Y member 1G isoform X2

    Conserved Domains (1) summary
    cd15947
    Location:8 → 249
    7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_017314558.2 → XP_017170047.1  olfactory receptor family 2 subfamily Y member 1G isoform X1

    Conserved Domains (1) summary
    cd15947
    Location:7 → 257
    7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_006533360.3 → XP_006533423.1  olfactory receptor family 2 subfamily Y member 1G isoform X1

    See identical proteins and their annotated locations for XP_006533423.1

    Conserved Domains (1) summary
    cd15947
    Location:7 → 257
    7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_017314560.2 → XP_017170049.1  olfactory receptor family 2 subfamily Y member 1G isoform X2

    Conserved Domains (1) summary
    cd15947
    Location:8 → 249
    7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_030246012.1 → XP_030101872.1  olfactory receptor family 2 subfamily Y member 1G isoform X1

    Conserved Domains (1) summary
    cd15947
    Location:7 → 257
    7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

  6. XM_030246011.1 → XP_030101871.1  olfactory receptor family 2 subfamily Y member 1G isoform X1

    Conserved Domains (1) summary
    cd15947
    Location:7 → 257
    7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

  7. XM_017314559.2 → XP_017170048.1  olfactory receptor family 2 subfamily Y member 1G isoform X1

    Conserved Domains (1) summary
    cd15947
    Location:7 → 257
    7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_003949443.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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