Or4a69 olfactory receptor family 4 subfamily A member 69 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Or4a69provided by MGI
Official Full Name: olfactory receptor family 4 subfamily A member 69provided by MGI
Primary source: MGI:MGI:3031075
See related: Ensembl:ENSMUSG00000075086 AllianceGenome:MGI:3031075
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Olfr1241; MOR231-14
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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Genomic context

Location:: 2 E1; 2 50.06 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (89307628..89313477, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (89477284..89483133, complement)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

This odorant receptor, Olfr1241, responds to the odorant whiskey lactone in vivo
Title: Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	ISA Inferred from Sequence Alignment more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	ISA Inferred from Sequence Alignment more info	PubMed
acts_upstream_of_or_within sensory perception of smell	ISA Inferred from Sequence Alignment more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	ISA Inferred from Sequence Alignment more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: olfactory receptor family 4 subfamily A member 69

Names: GA_x6K02T2Q125-50926215-50925271; olfactory receptor 1241; olfactory receptor MOR231-14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_146455.1 → NP_666666.1 olfactory receptor family 4 subfamily A member 69

See identical proteins and their annotated locations for NP_666666.1

Status: PROVISIONAL

Source sequence(s)

AY073643

Consensus CDS

CCDS16381.1

UniProtKB/TrEMBL

Q8VF91

Related

ENSMUSP00000097366.2, ENSMUST00000099778.2

Conserved Domains (2) summary

pfam00001
Location:39 → 285

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:29 → 300

7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000068.8 Reference GRCm39 C57BL/6J

Range

89307628..89313477 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017318414.1 → XP_017173903.1 olfactory receptor family 4 subfamily A member 69 isoform X1

Conserved Domains (1) summary

cd15939
Location:23 → 289

7tmA_OR4A-like; olfactory receptor 4A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors