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Or5ak24 olfactory receptor family 5 subfamily AK member 24 [ Mus musculus (house mouse) ]

Gene ID: 258425, updated on 2-Nov-2024

Summary

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Official Symbol
Or5ak24provided by MGI
Official Full Name
olfactory receptor family 5 subfamily AK member 24provided by MGI
Primary source
MGI:MGI:3030828
See related
Ensembl:ENSMUSG00000075219 AllianceGenome:MGI:3030828
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Olfr994; MOR203-4
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Or5ak24 in Genome Data Viewer
Location:
2 D; 2 49.68 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (85260227..85266537, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (85429883..85436193, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily AK member 23 Neighboring gene predicted gene, 23716 Neighboring gene STARR-seq mESC enhancer starr_05015 Neighboring gene STARR-seq mESC enhancer starr_05016 Neighboring gene olfactory receptor family 5 subfamily AK member 25 Neighboring gene STARR-seq mESC enhancer starr_05017 Neighboring gene fatty acid desaturase 2B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  2. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  3. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
  4. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
involved_in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 

General protein information

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Preferred Names
olfactory receptor family 5 subfamily AK member 24
Names
GA_x6K02T2Q125-46907515-46906571
olfactory receptor 994
olfactory receptor MOR203-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146433.1 → NP_666644.1  olfactory receptor family 5 subfamily AK member 24

    See identical proteins and their annotated locations for NP_666644.1

    Status: PROVISIONAL

    Source sequence(s)
    AY073665
    Consensus CDS
    CCDS16207.1
    UniProtKB/TrEMBL
    Q8VF73
    Related
    ENSMUSP00000097509.2, ENSMUST00000099925.2
    Conserved Domains (2) summary
    cd14964
    Location:27 → 51
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:12 → 297
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    85260227..85266537 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006499549.2 → XP_006499612.1  olfactory receptor family 5 subfamily AK member 24 isoform X1

    See identical proteins and their annotated locations for XP_006499612.1

    UniProtKB/TrEMBL
    Q8VF73
    Related
    ENSMUSP00000151122.2, ENSMUST00000214679.2
    Conserved Domains (2) summary
    cd14964
    Location:27 → 51
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:12 → 297
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein Strain
Heading Accession and Version

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