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Or4a80 olfactory receptor family 4 subfamily A member 80 [ Mus musculus (house mouse) ]

Gene ID: 258370, updated on 2-Nov-2024

Summary

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Official Symbol
Or4a80provided by MGI
Official Full Name
olfactory receptor family 4 subfamily A member 80provided by MGI
Primary source
MGI:MGI:3031393
See related
Ensembl:ENSMUSG00000075075 AllianceGenome:MGI:3031393
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Olfr1253; MOR231-18; MOR231-19P; Olfr1253-ps1; Olfr1559-ps1
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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Genomic context

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See Or4a80 in Genome Data Viewer
Location:
2 E1; 2 50.12 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (89582214..89583170, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (89751870..89752826, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily A member 78 Neighboring gene olfactory receptor family 4 subfamily A member 79 Neighboring gene olfactory receptor family 4 subfamily A member 81 Neighboring gene olfactory receptor family 4 subfamily C member 12B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  2. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  3. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
  4. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor 1253
Names
GA_x6K02T2Q125-51193814-51192857
olfactory receptor 1253, pseudogene 1
olfactory receptor 1559, pseudogene 1
olfactory receptor MOR231-18
olfactory receptor MOR231-19P

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146373.1 → NP_666485.1  olfactory receptor 1253

    See identical proteins and their annotated locations for NP_666485.1

    Status: VALIDATED

    Source sequence(s)
    AL929065
    Consensus CDS
    CCDS50628.1
    UniProtKB/TrEMBL
    A2AUA2, Q7TQZ4
    Related
    ENSMUSP00000097353.2, ENSMUST00000099765.2
    Conserved Domains (2) summary
    pfam00001
    Location:39 → 285
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29 → 300
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    89582214..89583170 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_003231.2: Suppressed sequence

    Description
    NG_003231.2: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
Nucleotide Protein
Heading Accession and Version

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