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Or1i2 olfactory receptor family 1 subfamily I member 1 [ Mus musculus (house mouse) ]

Gene ID: 257883, updated on 2-Nov-2024

Summary

Official Symbol
Or1i2provided by MGI
Official Full Name
olfactory receptor family 1 subfamily I member 1provided by MGI
Primary source
MGI:MGI:3031191
See related
Ensembl:ENSMUSG00000071185 AllianceGenome:MGI:3031191
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MOR128-3; MOR128-4; Olfr1357
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Or1i2 in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78447503..78453908, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78611669..78618074, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene ilvB (bacterial acetolactate synthase)-like Neighboring gene synapse defective 1, Rho GTPase, homolog 1 (C. elegans) Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:78057364-78057547 Neighboring gene predicted gene, 30346 Neighboring gene L-2-hydroxyglutarate dehydrogenase pseudogene Neighboring gene predicted gene, 47459

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
PubMed 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
olfactory receptor 1357
Names
GA_x6K02T2QGN0-3196801-3197742
olfactory receptor MOR128-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011737.2NP_001011737.1  olfactory receptor 1357

    See identical proteins and their annotated locations for NP_001011737.1

    Status: VALIDATED

    Source sequence(s)
    AC153887
    Consensus CDS
    CCDS23968.1
    UniProtKB/TrEMBL
    A0A0N4SVB6, Q7TQU7
    Related
    ENSMUSP00000093127.3, ENSMUST00000095473.6
    Conserved Domains (2) summary
    pfam00001
    Location:41290
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:31304
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    78447503..78453908 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)