Hmgb1 high mobility group box 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 25459, updated on 2-Nov-2024

Summary

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Symbol: Hmgb1provided by RGD
Full Name: high mobility group box 1provided by RGD
Primary source: RGD:2802
See related: AllianceGenome:RGD:2802
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Hmg1; Ac2-008
Summary: Enables several functions, including DNA binding activity; heparin binding activity; and signaling receptor binding activity. Involved in several processes, including positive regulation of cytokine production; regulation of DNA metabolic process; and response to bacterium. Acts upstream of or within several processes, including DNA geometric change; induction of positive chemotaxis; and positive regulation of mesenchymal cell proliferation. Located in cytosol; extracellular space; and membrane raft. Used to study artery disease (multiple); brain infarction; congestive heart failure; high grade glioma; and sciatic neuropathy. Biomarker of several diseases, including atherosclerosis; colon adenocarcinoma; hydrocephalus; middle cerebral artery infarction; and obstructive jaundice. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human HMGB1 (high mobility group box 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

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See Hmgb1 in Genome Data Viewer

Location:: 12p11

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	12	NC_086030.1 (11009236..11015941)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	12	NC_051347.1 (5972950..5979658)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	12	NC_005111.4 (7082529..7090246)

Chromosome 12 - NC_086030.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

METTL3 mediated ferroptosis in chondrocytes and promoted pain in KOA via HMGB1 m6A modification.
Title: METTL3 mediated ferroptosis in chondrocytes and promoted pain in KOA via HMGB1 m6A modification.
SIRT1-Mediated HMGB1 Deacetylation Suppresses Neutrophil Extracellular Traps Related to Blood-Brain Barrier Impairment After Cerebral Venous Thrombosis.
Title: SIRT1-Mediated HMGB1 Deacetylation Suppresses Neutrophil Extracellular Traps Related to Blood-Brain Barrier Impairment After Cerebral Venous Thrombosis.
Box A of HMGB1 Maintains the DNA Gap and Prevents DDR-induced Kidney Injury in D-galactose Induction Rats.
Title: Box A of HMGB1 Maintains the DNA Gap and Prevents DDR-induced Kidney Injury in D-galactose Induction Rats.
HMGB1 Mediates Inflammation-Induced DMT1 Increase and Dopaminergic Neurodegeneration in the Early Stage of Parkinsonism.
Title: HMGB1 Mediates Inflammation-Induced DMT1 Increase and Dopaminergic Neurodegeneration in the Early Stage of Parkinsonism.
Suppression of microRNA-320 Induces Cerebral Protection Against Ischemia/Reperfusion Injury by Targeting HMGB1/NF-kappaB Axis.
Title: Suppression of microRNA-320 Induces Cerebral Protection Against Ischemia/Reperfusion Injury by Targeting HMGB1/NF-kappaB Axis.
Influences of microRNA-451 on the expression of HMGB1 in myocardial cells and its mechanism in ischemia-reperfusion injury.
Title: Influences of microRNA-451 on the expression of HMGB1 in myocardial cells and its mechanism in ischemia-reperfusion injury.
Inhibition of HMGB1 Attenuates Spinal Cord Edema by Reducing the Expression of Na[+]-K[+]-Cl[-] Cotransporter-1 and Na[+]/H[+] Exchanger-1 in Both Astrocytes and Endothelial Cells After Spinal Cord Injury in Rats.
Title: Inhibition of HMGB1 Attenuates Spinal Cord Edema by Reducing the Expression of Na(+)-K(+)-Cl(-) Cotransporter-1 and Na(+)/H(+) Exchanger-1 in Both Astrocytes and Endothelial Cells After Spinal Cord Injury in Rats.
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
Title: Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
Hmgb1 Silencing in the Amygdala Inhibits Pain-Related Behaviors in a Rat Model of Neuropathic Pain.
Title: Hmgb1 Silencing in the Amygdala Inhibits Pain-Related Behaviors in a Rat Model of Neuropathic Pain.
HMGB1-induced activation of ER stress contributes to pulmonary artery hypertension in vitro and in vivo.
Title: HMGB1-induced activation of ER stress contributes to pulmonary artery hypertension in vitro and in vivo.

Submit: New GeneRIF Correction See all GeneRIFs (274)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

BE097853 (e-PCR)
- UniSTS:244767

RH130603 (e-PCR)
- UniSTS:213887

GDB:554977 (e-PCR)
- UniSTS:157665

Hmgb1 (e-PCR), detects polymorphism
- UniSTS:143350

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables 5S rRNA binding	IDA Inferred from Direct Assay more info	PubMed
enables C-X-C chemokine binding	ISO Inferred from Sequence Orthology more info
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA binding, bending	IBA Inferred from Biological aspect of Ancestor more info
enables DNA binding, bending	IDA Inferred from Direct Assay more info	PubMed
enables DNA binding, bending	ISO Inferred from Sequence Orthology more info
enables DNA polymerase binding	ISO Inferred from Sequence Orthology more info
enables DNA-binding transcription factor binding	ISO Inferred from Sequence Orthology more info
enables RAGE receptor binding	IMP Inferred from Mutant Phenotype more info	PubMed
enables RAGE receptor binding	IPI Inferred from Physical Interaction more info	PubMed
enables RNA polymerase II-specific DNA-binding transcription factor binding	ISO Inferred from Sequence Orthology more info
enables bent DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables bubble DNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables calcium-dependent protein kinase regulator activity	ISO Inferred from Sequence Orthology more info
enables crossed form four-way junction DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables cytokine activity	IDA Inferred from Direct Assay more info	PubMed
enables cytokine activity	ISO Inferred from Sequence Orthology more info
enables damaged DNA binding	ISO Inferred from Sequence Orthology more info
enables double-stranded DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables double-stranded DNA binding	ISO Inferred from Sequence Orthology more info
enables double-stranded RNA binding	ISO Inferred from Sequence Orthology more info
enables four-way junction DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables glycolipid binding	IDA Inferred from Direct Assay more info	PubMed
enables heparin binding	IDA Inferred from Direct Assay more info	PubMed
enables heparin binding	TAS Traceable Author Statement more info	PubMed
enables integrin binding	ISO Inferred from Sequence Orthology more info
enables lipopolysaccharide binding	ISO Inferred from Sequence Orthology more info
enables lyase activity	ISO Inferred from Sequence Orthology more info
enables non-sequence-specific DNA binding, bending	ISO Inferred from Sequence Orthology more info
enables nucleic acid binding	ISO Inferred from Sequence Orthology more info
enables open form four-way junction DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables peptide binding	IDA Inferred from Direct Assay more info	PubMed
enables phosphatidylserine binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein heterodimerization activity	EXP Inferred from Experiment more info	PubMed
enables protein kinase activator activity	ISO Inferred from Sequence Orthology more info
enables receptor ligand activity	ISO Inferred from Sequence Orthology more info
enables single-stranded DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables single-stranded RNA binding	ISO Inferred from Sequence Orthology more info
enables supercoiled DNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables transcription cis-regulatory region binding	ISO Inferred from Sequence Orthology more info
enables transcription coactivator activity	ISO Inferred from Sequence Orthology more info
enables transcription corepressor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA geometric change	IDA Inferred from Direct Assay more info	PubMed
involved_in DNA recombination	IEA Inferred from Electronic Annotation more info
involved_in DNA repair	IEA Inferred from Electronic Annotation more info
involved_in MyD88-dependent toll-like receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in T-helper 1 cell activation	ISO Inferred from Sequence Orthology more info
involved_in T-helper 1 cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in V(D)J recombination	ISO Inferred from Sequence Orthology more info
involved_in actin cytoskeleton organization	IDA Inferred from Direct Assay more info	PubMed
involved_in activation of innate immune response	ISO Inferred from Sequence Orthology more info
involved_in apoptotic cell clearance	ISO Inferred from Sequence Orthology more info
involved_in apoptotic cell clearance	ISS Inferred from Sequence or Structural Similarity more info
involved_in autophagy	IEA Inferred from Electronic Annotation more info
involved_in base-excision repair	ISO Inferred from Sequence Orthology more info
involved_in cell morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cellular response to interleukin-1	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within cellular response to interleukin-7	ISO Inferred from Sequence Orthology more info
involved_in cellular response to lipopolysaccharide	ISO Inferred from Sequence Orthology more info
involved_in chemotaxis	IDA Inferred from Direct Assay more info	PubMed
involved_in chemotaxis	IEA Inferred from Electronic Annotation more info
involved_in chromatin organization	ISO Inferred from Sequence Orthology more info
involved_in circadian rhythm	IEP Inferred from Expression Pattern more info	PubMed
involved_in double-strand break repair via nonhomologous end joining	ISO Inferred from Sequence Orthology more info
involved_in endothelial cell chemotaxis	ISO Inferred from Sequence Orthology more info
involved_in endothelial cell proliferation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within eye development	ISO Inferred from Sequence Orthology more info
acts_upstream_of glycogen catabolic process	ISO Inferred from Sequence Orthology more info
involved_in heterochromatin formation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within induction of positive chemotaxis	IDA Inferred from Direct Assay more info	PubMed
involved_in inflammatory response	ISO Inferred from Sequence Orthology more info
involved_in inflammatory response to antigenic stimulus	ISO Inferred from Sequence Orthology more info
involved_in innate immune response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lung development	ISO Inferred from Sequence Orthology more info
involved_in macrophage activation involved in immune response	ISO Inferred from Sequence Orthology more info
involved_in male-specific defense response to bacterium	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of myeloid cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in myeloid dendritic cell activation	ISO Inferred from Sequence Orthology more info
acts_upstream_of myeloid progenitor cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in myoblast proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of CD4-positive, alpha-beta T cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of DNA replication	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of RNA polymerase II transcription preinitiation complex assembly	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of apoptotic cell clearance	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of blood vessel endothelial cell migration	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of type II interferon production	ISO Inferred from Sequence Orthology more info
involved_in nervous system development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuron apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuron projection development	IGI Inferred from Genetic Interaction more info	PubMed
involved_in neutrophil clearance	ISO Inferred from Sequence Orthology more info
involved_in neutrophil clearance	ISS Inferred from Sequence or Structural Similarity more info
involved_in nucleosome assembly	ISO Inferred from Sequence Orthology more info
involved_in plasmacytoid dendritic cell activation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of DNA ligase activity	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of DNA ligation	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of ERK1 and ERK2 cascade	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of JNK cascade	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of MAPK cascade	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of activated T cell proliferation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of autophagy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of autophagy	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of blood vessel endothelial cell migration	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of cell migration	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of cell population proliferation	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of chemokine (C-X-C motif) ligand 2 production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cytosolic calcium ion concentration	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of dendritic cell differentiation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of glycogen catabolic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of innate immune response	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of interferon-alpha production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of interferon-beta production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of interleukin-1 beta production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of interleukin-1 production	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of interleukin-1 production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of interleukin-10 production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of interleukin-12 production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of interleukin-6 production	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of interleukin-6 production	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of interleukin-6 production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of interleukin-8 production	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of interleukin-8 production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of macrophage inflammatory protein 1 alpha production	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within positive regulation of mesenchymal cell proliferation	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of mismatch repair	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of mitotic cell cycle	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of monocyte chemotactic protein-1 production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of monocyte chemotaxis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of myeloid cell apoptotic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within positive regulation of myeloid cell differentiation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of myeloid progenitor cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of myoblast differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of neuron projection development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of non-canonical NF-kappaB signal transduction	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of protein phosphorylation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of smooth muscle cell migration	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of sprouting angiogenesis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of toll-like receptor 2 signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of toll-like receptor 4 signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of toll-like receptor 9 signaling pathway	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of tumor necrosis factor production	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of tumor necrosis factor production	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of tumor necrosis factor production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of vascular endothelial cell proliferation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of wound healing	ISO Inferred from Sequence Orthology more info
involved_in protein-containing complex assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of T cell mediated immune response to tumor cell	ISO Inferred from Sequence Orthology more info
involved_in regulation of T cell mediated immune response to tumor cell	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of nucleotide-excision repair	ISO Inferred from Sequence Orthology more info
involved_in regulation of restriction endodeoxyribonuclease activity	ISO Inferred from Sequence Orthology more info
involved_in regulation of tolerance induction	ISO Inferred from Sequence Orthology more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within response to glucocorticoid	ISO Inferred from Sequence Orthology more info
involved_in response to glucose	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to insulin	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to lipopolysaccharide	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to type II interferon	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to xenobiotic stimulus	IEP Inferred from Expression Pattern more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info
involved_in toll-like receptor 2 signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in toll-like receptor 4 signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of alphav-beta3 integrin-HMGB1 complex	ISO Inferred from Sequence Orthology more info
located_in cell surface	ISO Inferred from Sequence Orthology more info
located_in chromatin	ISO Inferred from Sequence Orthology more info
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in condensed chromosome	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in early endosome	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum-Golgi intermediate compartment	IEA Inferred from Electronic Annotation more info
located_in extracellular space	IDA Inferred from Direct Assay more info	PubMed
is_active_in extracellular space	ISO Inferred from Sequence Orthology more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
located_in membrane raft	IDA Inferred from Direct Assay more info	PubMed
located_in neuron projection	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
part_of transcription repressor complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: high mobility group protein B1

Names: Ac2-008-like; HMG-1; amphoterin; heparin-binding protein p30; high mobility group 1; high mobility group protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_012963.4 → NP_037095.1 high mobility group protein B1

See identical proteins and their annotated locations for NP_037095.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000012

UniProtKB/Swiss-Prot

P63159, Q548R9

UniProtKB/TrEMBL

B4F758, D3ZXR5

Conserved Domains (2) summary

pfam00505
Location:95 → 162

HMG_box; HMG (high mobility group) box

pfam09011
Location:6 → 78

HMG_box_2; HMG-box domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086030.1 Reference GRCr8

Range

11009236..11015941

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063271081.1 → XP_063127151.1 high mobility group protein B1 isoform X1

UniProtKB/Swiss-Prot

P63159, Q548R9

UniProtKB/TrEMBL

B4F758
XM_063271080.1 → XP_063127150.1 high mobility group protein B1 isoform X1

UniProtKB/Swiss-Prot

P63159, Q548R9

UniProtKB/TrEMBL

B4F758
XM_039089112.2 → XP_038945040.1 high mobility group protein B1 isoform X1

UniProtKB/Swiss-Prot

P63159, Q548R9

UniProtKB/TrEMBL

B4F758, D3ZXR5

Conserved Domains (2) summary

pfam00505
Location:95 → 162

HMG_box; HMG (high mobility group) box

pfam09011
Location:6 → 78

HMG_box_2; HMG-box domain
XM_063271082.1 → XP_063127152.1 high mobility group protein B1 isoform X1

UniProtKB/Swiss-Prot

P63159, Q548R9

UniProtKB/TrEMBL

B4F758