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mid2 septin ring organizing protein [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542683, updated on 18-Sep-2024

Summary

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Official Symbol
mid2
Official Full Name
septin ring organizing protein
Primary source
PomBase:SPAPYUG7.03c
Locus tag
SPOM_SPAPYUG7.03C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See mid2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (4748861..4751453, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MAP kinase-interacting protein Sin1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA-directed RNA polymerase II complex TFIIS subunit Rpb9 Neighboring gene ncRNA Neighboring gene delta-1-pyrroline-5-carboxylate reductase Neighboring gene PPPDE peptidase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An anillin homologue, Mid2p, acts during fission yeast cytokinesis to organize the septin ring and promote cell separation. Tasto JJ, et al. J Cell Biol, 2003 Mar 31. PMID 12668659, Free PMC Article
  2. Mid2p stabilizes septin rings during cytokinesis in fission yeast. Berlin A, et al. J Cell Biol, 2003 Mar 31. PMID 12654901, Free PMC Article
  3. Mid1p/anillin and the septation initiation network orchestrate contractile ring assembly for cytokinesis. Hachet O, et al. Genes Dev, 2008 Nov 15. PMID 19056897, Free PMC Article
  4. Ace2p contributes to fission yeast septin ring assembly by regulating mid2+ expression. Petit CS, et al. J Cell Sci, 2005 Dec 15. PMID 16317047
  5. Role of septins and the exocyst complex in the function of hydrolytic enzymes responsible for fission yeast cell separation. Martín-Cuadrado AB, et al. Mol Biol Cell, 2005 Oct. PMID 16079182, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that Mid1p/anillin and the septation initiation network orchestrate contractile ring assembly for cytokinesis.
    Title: Mid1p/anillin and the septation initiation network orchestrate contractile ring assembly for cytokinesis.
  2. Mid2p production is controlled by Ace2p functioning downstream of Sep1p.
    Title: Ace2p contributes to fission yeast septin ring assembly by regulating mid2+ expression.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables GTP binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables phosphatidylinositol-4,5-bisphosphate binding TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in septin ring organization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in septin ring organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell division site HDA PubMed 
is_active_in cytoplasm HDA PubMed 
is_active_in cytosol HDA PubMed 
is_active_in medial cortex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in medial cortex septin ring IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in split septin rings IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
septin ring organizing protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4748861..4751453 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020131.3 → NP_594704.2  septin ring organizing protein [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594704.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q8X1T2, Q9P7Y8
    Conserved Domains (2) summary
    cd13278
    Location:567 → 699
    PH_Bud4; Bud4 Pleckstrin homology (PH) domain
    pfam00169
    Location:584 → 687
    PH; PH domain
Nucleotide Protein
Heading Accession and Version

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