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hxk1 hexokinase 1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542634, updated on 18-Sep-2024

Summary

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Official Symbol
hxk1
Official Full Name
hexokinase 1
Primary source
PomBase:SPAC24H6.04
Locus tag
SPOM_SPAC24H6.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See hxk1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (482607..485184, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA replication pre-initiation complex subunit Sld3 Neighboring gene protein tyrosine phosphatase (M phase inducer) Cdc25 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cullin 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Purification and kinetic characterization of hexokinase and glucose-6-phosphate dehydrogenase from Schizosaccharomyces pombe. Tsai CS, et al. Biochem Cell Biol, 1998. PMID 9666312
  2. A mutation Ser213/Asn in the hexokinase 1 from Schizosaccharomyces pombe increases its affinity for glucose. Petit T, et al. Biochem Biophys Res Commun, 1998 Oct 29. PMID 9790975
  3. Schizosaccharomyces pombe possesses an unusual and a conventional hexokinase: biochemical and molecular characterization of both hexokinases. Petit T, et al. FEBS Lett, 1996 Jan 8. PMID 8549830
  4. Global coordination of transcriptional control and mRNA decay during cellular differentiation. Amorim MJ, et al. Mol Syst Biol, 2010 Jun 8. PMID 20531409, Free PMC Article
  5. A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast. Mathiassen SG, et al. J Biol Chem, 2015 Aug 21. PMID 26152728, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISM
Inferred from Sequence Model
more info
  
enables D-glucose binding IEA
Inferred from Electronic Annotation
more info
  
enables fructokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables fructokinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glucokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucokinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables hexokinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables mannokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mannokinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical glycolysis IC
Inferred by Curator
more info
 PubMed 
involved_in fructose metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in glucose 6-phosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glucose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glucose metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in glycolytic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular glucose homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mannose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mannose metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in pentose-phosphate shunt, oxidative branch TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
hexokinase 1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    482607..485184 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018349.3 → NP_592948.1  hexokinase 1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_592948.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q09756
    Conserved Domains (3) summary
    COG5026
    Location:10 → 474
    COG5026; Hexokinase [Carbohydrate transport and metabolism]
    pfam00349
    Location:30 → 224
    Hexokinase_1; Hexokinase
    pfam03727
    Location:230 → 466
    Hexokinase_2; Hexokinase
Nucleotide Protein
Heading Accession and Version

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