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mtl16 methyltransferase Mtl16 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542223, updated on 18-Sep-2024

Summary

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Official Symbol
mtl16
Official Full Name
methyltransferase Mtl16
Primary source
PomBase:SPAC27D7.08c
Locus tag
SPOM_SPAC27D7.08C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See mtl16 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003424.3 (4521375..4523080, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene electron transfer flavoprotein alpha subunit Neighboring gene ncRNA Neighboring gene Sm snRNP core protein Smd1 Neighboring gene ncRNA Neighboring gene But2 family protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library. Pan X, et al. BMC Genomics, 2012 Nov 23. PMID 23173672, Free PMC Article
  2. The U6 snRNA m(6)A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. Pendleton KE, et al. Cell, 2017 May 18. PMID 28525753, Free PMC Article
  3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables 23S rRNA (adenine(1618)-N(6))-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables U6 snRNA (adenine-(43)-N(6))-methyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in rRNA base methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in snRNA (adenine-N6)-methylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
methyltransferase Mtl16

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4521375..4523080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020042.3 → NP_594614.1  methyltransferase Mtl16 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594614.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42662
    Conserved Domains (1) summary
    cl17173
    Location:1 → 373
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
Nucleotide Protein
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