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hus5 small ubiquitin-like modifier-conjugating enzyme Hus5 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542196, updated on 18-Sep-2024

Summary

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Official Symbol
hus5
Official Full Name
small ubiquitin-like modifier-conjugating enzyme Hus5
Primary source
PomBase:SPAC30D11.13
Locus tag
SPOM_SPAC30D11.13
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
ubc9
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Genomic context

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See hus5 in Genome Data Viewer
Location:
chromosome: I
Exon count:
6
Sequence:
Chromosome: I; NC_003424.3 (1094262..1095474, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Moeb/ThiF domain-containing protein Neighboring gene RNA-binding protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Ser Neighboring gene tRNA-Met Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular mimicry of SUMO promotes DNA repair. Prudden J, et al. Nat Struct Mol Biol, 2009 May. PMID 19363481, Free PMC Article
  2. SUMO modification is involved in the maintenance of heterochromatin stability in fission yeast. Shin JA, et al. Mol Cell, 2005 Sep 16. PMID 16168376
  3. Characterization of SUMO-conjugating enzyme mutants in Schizosaccharomyces pombe identifies a dominant-negative allele that severely reduces SUMO conjugation. Ho JC, et al. Biochem J, 2003 May 15. PMID 12597774, Free PMC Article
  4. Role of the fission yeast SUMO E3 ligase Pli1p in centromere and telomere maintenance. Xhemalce B, et al. EMBO J, 2004 Oct 1. PMID 15359282, Free PMC Article
  5. The Schizosaccharomyces pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis. al-Khodairy F, et al. J Cell Sci, 1995 Feb. PMID 7768995

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IC
Inferred by Curator
more info
  
enables SUMO activating enzyme activity TAS
Traceable Author Statement
more info
 PubMed 
enables SUMO conjugating enzyme activity EXP
Inferred from Experiment
more info
 PubMed 
enables SUMO conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables SUMO conjugating enzyme activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA repair IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in protein sumoylation EXP
Inferred from Experiment
more info
 PubMed 
involved_in protein sumoylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein sumoylation IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
small ubiquitin-like modifier-conjugating enzyme Hus5

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1094262..1095474 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018600.3 → NP_593204.1  small ubiquitin-like modifier-conjugating enzyme Hus5 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593204.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P40984
    Conserved Domains (2) summary
    COG5078
    Location:1 → 156
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    pfam00179
    Location:8 → 152
    UQ_con; Ubiquitin-conjugating enzyme
Nucleotide Protein
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