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cop1 coatomer alpha subunit protein [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541412, updated on 18-Sep-2024

Summary

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Official Symbol
cop1
Official Full Name
coatomer alpha subunit protein
Primary source
PomBase:SPBPJ4664.04
Locus tag
SPOM_SPBPJ4664.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See cop1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (701831..705817)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene M-factor precursor Mfm3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene UDP-glucose--glycoprotein glucosyltransferase Gpt1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking. Dey D, et al. Commun Biol, 2022 Feb 8. PMID 35136165, Free PMC Article
  2. Rules for the recognition of dilysine retrieval motifs by coatomer. Ma W, et al. EMBO J, 2013 Apr 3. PMID 23481256, Free PMC Article
  3. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article
  4. Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase. Chen JS, et al. Mol Cell Proteomics, 2013 May. PMID 23297348, Free PMC Article
  5. SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast. Singh NS, et al. Curr Biol, 2011 Dec 6. PMID 22119525, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables cargo receptor activity EXP
Inferred from Experiment
more info
 PubMed 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of COPI vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in Golgi apparatus HDA PubMed 
is_active_in cytoplasm HDA PubMed 

General protein information

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Preferred Names
coatomer alpha subunit protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    701831..705817
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021186.3 → NP_595279.1  coatomer alpha subunit protein [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595279.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q96WV5
    Conserved Domains (5) summary
    COG2319
    Location:1 → 508
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:17 → 325
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    pfam04053
    Location:347 → 774
    Coatomer_WDAD; Coatomer WD associated region
    pfam06957
    Location:858 → 1204
    COPI_C; Coatomer (COPI) alpha subunit C-terminus
    sd00039
    Location:17 → 51
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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