U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

skp1 SCF ubiquitin ligase complex subunit Skp1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540917, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
skp1
Official Full Name
SCF ubiquitin ligase complex subunit Skp1
Primary source
PomBase:SPBC409.05
Locus tag
SPOM_SPBC409.05
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
psh1; sph1
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See skp1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003423.3 (1140128..1141240)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MIS12/MIND complex Mis12 Neighboring gene ncRNA Neighboring gene protein Swi5 Neighboring gene ncRNA Neighboring gene ubiquitin hydrolase Uch2 Neighboring gene ncRNA Neighboring gene MAP kinase kinase Wis1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Fission yeast Skp1 is required for spindle morphology and nuclear membrane segregation at anaphase. Lehmann A, et al. FEBS Lett, 2004 May 21. PMID 15147872
  2. Essential and distinct roles of the F-box and helicase domains of Fbh1 in DNA damage repair. Sakaguchi C, et al. BMC Mol Biol, 2008 Mar 3. PMID 18312697, Free PMC Article
  3. Skp1 and the F-box protein Pof6 are essential for cell separation in fission yeast. Hermand D, et al. J Biol Chem, 2003 Mar 14. PMID 12511573
  4. Identification of a conserved F-box protein 6 interactor essential for endocytosis and cytokinesis in fission yeast. Jourdain I, et al. Biochem J, 2009 May 13. PMID 19243310, Free PMC Article
  5. Fission yeast Mcl1 interacts with SCF(Pof3) and is required for centromere formation. Mamnun YM, et al. Biochem Biophys Res Commun, 2006 Nov 10. PMID 16997270

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables cullin family protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic nuclear membrane biogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nuclear envelope organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA recombination IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in resolution of meiotic recombination intermediates IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of RAVE complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
part_of nuclear SCF ubiquitin ligase complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of single-stranded DNA-dependent ATP-dependent DNA helicase complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
SCF ubiquitin ligase complex subunit Skp1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1140128..1141240
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021365.3 → NP_595455.1  SCF ubiquitin ligase complex subunit Skp1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595455.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9Y709
    Conserved Domains (3) summary
    smart00512
    Location:1 → 110
    Skp1; Found in Skp1 protein family
    COG5201
    Location:1 → 161
    SKP1; SCF ubiquitin ligase, SKP1 component [Posttranslational modification, protein turnover, chaperones]
    pfam01466
    Location:84 → 158
    Skp1; Skp1 family, dimerization domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.