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lsm3 U6 snRNP-associated protein Lsm3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540212, updated on 18-Sep-2024

Summary

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Official Symbol
lsm3
Official Full Name
U6 snRNP-associated protein Lsm3
Primary source
PomBase:SPBC9B6.05c
Locus tag
SPOM_SPBC9B6.05C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See lsm3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003423.3 (1821460..1822728, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene zf-FYVE type zinc finger protein and glutamine sensor Pib2 Neighboring gene ncRNA Neighboring gene translation elongation factor EF-Tu Tuf1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein uL15m Neighboring gene Nop52 family nucleolar protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Quality-Control Mechanism for Telomerase RNA Folding in the Cell. Hu X, et al. Cell Rep, 2020 Dec 29. PMID 33378677
  2. LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast. Mennie AK, et al. Nat Commun, 2018 Feb 8. PMID 29422503, Free PMC Article
  3. Crystal structures of Lsm3, Lsm4 and Lsm5/6/7 from Schizosaccharomyces pombe. Wu D, et al. PLoS One, 2012. PMID 22615807, Free PMC Article
  4. Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Montemayor EJ, et al. RNA, 2020 Oct. PMID 32518066, Free PMC Article
  5. LARP7 family proteins have conserved function in telomerase assembly. Collopy LC, et al. Nat Commun, 2018 Feb 8. PMID 29422501, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to RNA folding chaperone EXP
Inferred from Experiment
more info
 PubMed 
enables U2 snRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables chromatin binding IDA
Inferred from Direct Assay
more info
 PubMed 
contributes_to poly(U) RNA binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables telomerase RNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in P-body assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Lsm1-7-Pat1 complex EXP
Inferred from Experiment
more info
 PubMed 
part_of Lsm1-7-Pat1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Lsm2-8 complex EXP
Inferred from Experiment
more info
 PubMed 
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2 snRNP EXP
Inferred from Experiment
more info
 PubMed 
part_of U4/U6 x U5 tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U5 snRNP IDA
Inferred from Direct Assay
more info
 PubMed 
part_of U6 snRNP EXP
Inferred from Experiment
more info
 PubMed 
part_of U6 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in chromosome, telomeric repeat region IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in nucleus HDA PubMed 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of telomerase holoenzyme complex TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
U6 snRNP-associated protein Lsm3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1821460..1822728 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021647.3 → NP_595747.1  U6 snRNP-associated protein Lsm3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595747.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9Y7M4
    Conserved Domains (1) summary
    cd01730
    Location:9 → 90
    LSm3; Like-Sm protein 3
Nucleotide Protein
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