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act1 actin Act1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540051, updated on 18-Sep-2024

Summary

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Official Symbol
act1
Official Full Name
actin Act1
Primary source
PomBase:SPBC32H8.12c
Locus tag
SPOM_SPBC32H8.12C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
cps8
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Genomic context

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See act1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (1475485..1477333, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA-binding forkhead transcription factor, meiotic Mei4 Neighboring gene ncRNA Neighboring gene spore wall alpha-1,3-glucan synthase Mok12 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ultrastructure of cell wall of the cps8 actin mutant cell in Schizosaccharomyces pombe. Ishijima SA, et al. FEMS Microbiol Lett, 1999 Nov 1. PMID 10547441
  2. Fission yeast Adf1 is necessary for reassembly of actin filaments into the contractile ring during cytokinesis. Ueda EI, et al. Biochem Biophys Res Commun, 2018 Nov 25. PMID 30201262
  3. Molecular dissection of the actin-binding ability of the fission yeast α-actinin, Ain1, in vitro and in vivo. Morita R, et al. J Biochem, 2017 Aug 1. PMID 28338873
  4. Analysis of biophysical and functional consequences of tropomyosin-fluorescent protein fusions. Brooker HR, et al. FEBS Lett, 2016 Sep. PMID 27501521, Free PMC Article
  5. A molecular evolution approach to study the roles of tropomyosin in fission yeast. Cranz-Mileva S, et al. PLoS One, 2013. PMID 24167549, Free PMC Article

See all (61) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Adf1 is necessary for reassembly of actin filaments into the contractile ring during cytokinesis.
    Title: Fission yeast Adf1 is necessary for reassembly of actin filaments into the contractile ring during cytokinesis.
  2. Furthermore, Cdc8, Fim1, and Adf1 all compete for association with F-actin by different mechanisms, and their cooperative association with actin filaments affects their ability to compete.
    Title: Competition between Tropomyosin, Fimbrin, and ADF/Cofilin drives their sorting to distinct actin filament networks.
  3. Data indicate that the essential role of profilin is to specifically facilitate formin Cdc12-mediated actin assembly for cytokinesis.
    Title: Fission yeast profilin is tailored to facilitate actin assembly by the cytokinesis formin Cdc12.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural constituent of cytoskeleton NAS
Non-traceable Author Statement
more info
  
Process Evidence Code Pubs
involved_in DNA repair-dependent chromatin remodeling IC
Inferred by Curator
more info
  
involved_in chromatin remodeling IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in endocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcription initiation-coupled chromatin remodeling IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of Ino80 complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of Ino80 complex IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of NuA4 histone acetyltransferase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of Swr1 complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in actin cortical patch IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in actin filament TAS
Traceable Author Statement
more info
 PubMed 
is_active_in cell division site HDA PubMed 
is_active_in cell tip HDA PubMed 
is_active_in mating projection tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic actomyosin contractile ring, distal actin filament layer IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic actomyosin contractile ring, intermediate layer IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic actomyosin contractile ring, proximal layer IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in prospore membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
actin Act1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1475485..1477333 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021513.3 → NP_595618.1  actin Act1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595618.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P10989, Q10288
    Conserved Domains (2) summary
    smart00268
    Location:6 → 375
    ACTIN; Actin
    cl17037
    Location:1 → 375
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
Nucleotide Protein
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