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bfr1 plasma membrane brefeldin A efflux transporter Bfr1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539195, updated on 18-Sep-2024

Summary

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Official Symbol
bfr1
Official Full Name
plasma membrane brefeldin A efflux transporter Bfr1
Primary source
PomBase:SPCC18B5.01c
Locus tag
SPOM_SPCC18B5.01C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
hba2; SPCPJ732.04c
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Genomic context

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See bfr1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (709302..715418, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein meu15 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Bfr1p is responsible for tributyltin resistance in Schizosaccharomyces pombe. Akiyama K, et al. J Toxicol Sci, 2011 Jan. PMID 21297349
  2. Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome. Arita Y, et al. Mol Biosyst, 2011 May. PMID 21340088
  3. Genome-wide screen of genes required for caffeine tolerance in fission yeast. Calvo IA, et al. PLoS One, 2009 Aug 12. PMID 19672306, Free PMC Article
  4. Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology. Kawashima SA, et al. Chem Biol, 2012 Jul 27. PMID 22840777, Free PMC Article
  5. A survey of all 11 ABC transporters in fission yeast: two novel ABC transporters are required for red pigment accumulation in a Schizosaccharomyces pombe adenine biosynthetic mutant. Iwaki T, et al. Microbiology (Reading), 2006 Aug. PMID 16849797

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. It is responsible for tributyltin resistance in Schizosaccharomyces pombe.
    Title: Bfr1p is responsible for tributyltin resistance in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in xenobiotic detoxification by transmembrane export across the plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
plasma membrane brefeldin A efflux transporter Bfr1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    709302..715418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022923.4 → NP_587932.3  plasma membrane brefeldin A efflux transporter Bfr1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_587932.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O00035, P41820, P87254, Q09194, Q9C0U4, Q9USL8
    Conserved Domains (6) summary
    cd03232
    Location:879 → 1107
    ABCG_PDR_domain2; Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters
    cd03233
    Location:166 → 392
    ABCG_PDR_domain1; First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters
    TIGR00956
    Location:108 → 1516
    3a01205; Pleiotropic Drug Resistance (PDR) Family protein
    pfam01061
    Location:526 → 729
    ABC2_membrane; ABC-2 type transporter
    pfam06422
    Location:741 → 835
    PDR_CDR; CDR ABC transporter
    pfam14510
    Location:102 → 160
    ABC_trans_N; ABC-transporter extracellular N-terminal
Nucleotide Protein
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