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ung1 uracil DNA N-glycosylase Ung1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2538855, updated on 18-Sep-2024

Summary

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Official Symbol
ung1
Official Full Name
uracil DNA N-glycosylase Ung1
Primary source
PomBase:SPCC1183.06
Locus tag
SPOM_SPCC1183.06
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ung1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003421.2 (602974..604420)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene RNA metabolism pathway protein Pet127 Neighboring gene ncRNA Neighboring gene DNA repair ligase Lig4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Spo13

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A fission yeast homologue of the human uracil-DNA-glycosylase and their roles in causing DNA damage after overexpression. Elder RT, et al. Biochem Biophys Res Commun, 2003 Jul 4. PMID 12810074
  2. Tight coevolution of proliferating cell nuclear antigen (PCNA)-partner interaction networks in fungi leads to interspecies network incompatibility. Zamir L, et al. Proc Natl Acad Sci U S A, 2012 Feb 14. PMID 22308326, Free PMC Article
  3. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
  4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
  5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables uracil DNA N-glycosylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables uracil DNA N-glycosylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in base-excision repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in base-excision repair, AP site formation via deaminated base removal IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial DNA repair IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
uracil DNA N-glycosylase Ung1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    602974..604420
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022881.3 → NP_587889.1  uracil DNA N-glycosylase Ung1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_587889.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74834
    Conserved Domains (1) summary
    COG0692
    Location:80 → 304
    Ung; Uracil DNA glycosylase [Replication, recombination and repair]
Nucleotide Protein
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