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ZNF503-AS1 ZNF503 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 253264, updated on 22-Oct-2024

Summary

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Official Symbol
ZNF503-AS1provided by HGNC
Official Full Name
ZNF503 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:27370
See related
Ensembl:ENSG00000226051 AllianceGenome:HGNC:27370
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in esophagus (RPKM 2.0), colon (RPKM 1.7) and 21 other tissues See more
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Genomic context

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See ZNF503-AS1 in Genome Data Viewer
Location:
10q22.2
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (75296383..75361678)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (76169901..76235714)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (77056141..77121436)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein L39 pseudogene 25 Neighboring gene high mobility group AT-hook 1 pseudogene 5 Neighboring gene zinc finger protein 503 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2514 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2515 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:77142242-77143441 Neighboring gene uncharacterized LOC124902461 Neighboring gene sperm autoantigenic protein 17 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Involvement of long non-coding RNA ZNF503 antisense RNA 1 in diabetic retinopathy and its possible underlying mechanism. Han T, et al. Bioengineered, 2022 Jun. PMID 35734878, Free PMC Article
  2. LncRNA ZNF503-AS1 acts as a tumor suppressor in bladder cancer by up-regulating Ca(2+) concentration via transcription factor GATA6. He H, et al. Cell Oncol (Dordr), 2021 Feb. PMID 33001357
  3. LncRNA ZNF503-AS1 promotes RPE differentiation by downregulating ZNF503 expression. Chen X, et al. Cell Death Dis, 2017 Sep 7. PMID 28880276, Free PMC Article
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Brandenberger R, et al. Nat Biotechnol, 2004 Jun. PMID 15146197
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Involvement of long non-coding RNA ZNF503 antisense RNA 1 in diabetic retinopathy and its possible underlying mechanism.
    Title: Involvement of long non-coding RNA ZNF503 antisense RNA 1 in diabetic retinopathy and its possible underlying mechanism.
  2. LncRNA ZNF503-AS1 acts as a tumor suppressor in bladder cancer by up-regulating Ca(2+) concentration via transcription factor GATA6.
    Title: LncRNA ZNF503-AS1 acts as a tumor suppressor in bladder cancer by up-regulating Ca(2+) concentration via transcription factor GATA6.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

General gene information

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Markers

Other Names

  • ZNF503 antisense RNA 1 (non-protein coding)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_038223.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    AC010997, AK023445, CB997793
    Related
    ENST00000416398.2

  2. NR_038224.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AC010997, AK023445, CB997793
    Related
    ENST00000734881.1

  3. NR_038225.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an internal splice site resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AC010997, AK023445, CB997793, DA832441
    Related
    ENST00000734880.1

  4. NR_038226.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate splice site and contains an additional internal exon, compared to variant 1.
    Source sequence(s)
    AC010997, AK023445, CB997793, CN360505
    Related
    ENST00000533822.3

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    75296383..75361678
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    76169901..76235714
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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