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Timm13 translocase of inner mitochondrial membrane 13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 252928, updated on 2-Nov-2024

Summary

Official Symbol
Timm13provided by RGD
Official Full Name
translocase of inner mitochondrial membrane 13provided by RGD
Primary source
RGD:628845
See related
EnsemblRapid:ENSRNOG00000019682 AllianceGenome:RGD:628845
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in protein insertion into mitochondrial inner membrane. Predicted to be located in fibrillar center and mitochondrial inner membrane. Predicted to be part of mitochondrial intermembrane space protein transporter complex. Orthologous to human TIMM13 (translocase of inner mitochondrial membrane 13). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 382.9), Heart (RPKM 299.4) and 9 other tissues See more
Orthologs
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Genomic context

See Timm13 in Genome Data Viewer
Location:
7q11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (9459490..9460849)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (8809069..8810172)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11677340..11678443)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene growth arrest and DNA-damage-inducible, beta Neighboring gene uncharacterized LOC134479806 Neighboring gene lamin B2 Neighboring gene transmembrane serine protease 9 Neighboring gene uncharacterized LOC120093773 Neighboring gene signal peptide peptidase-like 2B

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in protein insertion into mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial intermembrane space protein transporter complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial intermembrane space protein transporter complex ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mitochondrial import inner membrane translocase subunit Tim13
Names
translocase of inner mitochondrial membrane 13 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145781.2NP_665724.1  mitochondrial import inner membrane translocase subunit Tim13

    See identical proteins and their annotated locations for NP_665724.1

    Status: VALIDATED

    Source sequence(s)
    AF144701, JAXUCZ010000007
    UniProtKB/Swiss-Prot
    P62076
    Related
    ENSRNOP00000099589.1, ENSRNOT00000026648.5
    Conserved Domains (1) summary
    pfam02953
    Location:2484
    zf-Tim10_DDP; Tim10/DDP family zinc finger

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    9459490..9460849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063263024.1XP_063119094.1  mitochondrial import inner membrane translocase subunit Tim13 isoform X1

    UniProtKB/Swiss-Prot
    P62076