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CG30288 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246531, updated on 2-Nov-2024

Summary

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Official Symbol
CG30288provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0050288
Locus tag
Dmel_CG30288
See related
AllianceGenome:FB:FBgn0050288
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG30288; SP225
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG30288 in Genome Data Viewer
Location:
57E9-57E9; 2-95 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21519243..21520393, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17406748..17407898, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene TATA box-binding protein-associated factor RNA polymerase I subunit C-like Neighboring gene Misexpression suppressor of KSR 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Epidermal growth factor receptor Neighboring gene long non-coding RNA:CR44725

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Host genetic determinants of microbiota-dependent nutrition revealed by genome-wide analysis of Drosophila melanogaster. Dobson AJ, et al. Nat Commun, 2015 Feb 18. PMID 25692519, Free PMC Article
  2. The Genetic Architecture of Ovariole Number in Drosophila melanogaster: Genes with Major, Quantitative, and Pleiotropic Effects. Lobell AS, et al. G3 (Bethesda), 2017 Jul 5. PMID 28550012, Free PMC Article
  3. Drosophila anti-nematode and antibacterial immune regulators revealed by RNA-Seq. Castillo JC, et al. BMC Genomics, 2015 Jul 11. PMID 26162375, Free PMC Article
  4. Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects. Cao X, et al. Insect Biochem Mol Biol, 2018 Dec. PMID 30367934, Free PMC Article
  5. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG30288-PC
NP_001097398.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    21519243..21520393 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001103928.2 → NP_001097398.1  uncharacterized protein Dmel_CG30288 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097398.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IRK6
    Conserved Domains (2) summary
    smart00020
    Location:42 → 270
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:45 → 270
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IRK6 Q8IRK6

Gene LinkOut

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