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AU018091 expressed sequence AU018091 [ Mus musculus (house mouse) ]

Gene ID: 245128, updated on 17-Aug-2024

Summary

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Official Symbol
AU018091provided by MGI
Official Full Name
expressed sequence AU018091provided by MGI
Primary source
MGI:MGI:2142124
See related
Ensembl:ENSMUSG00000054753 AllianceGenome:MGI:2142124
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
cat-5
Summary
Predicted to enable L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Predicted to be involved in L-arginine import across plasma membrane and L-ornithine transmembrane transport. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in placenta adult (RPKM 6.6) and testis adult (RPKM 1.5) See more
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Genomic context

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See AU018091 in Genome Data Viewer
Location:
7 A1; 7 1.84 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (3204498..3219029, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (3154658..3169203, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated glutamate (E)-rich protein 9, pseudogene 1 Neighboring gene zinc finger pseudogene Neighboring gene proteasome subunit beta type 5 precursor (proteasome epsilon chain) (Macropain epsilon chain) (multicatalytic endopeptidase complex epsilon chain) (proteasome subunit X) (proteasome chain 6) Neighboring gene STARR-seq mESC enhancer starr_17882 Neighboring gene CRISPRi-validated Mir290 enhancer cluster Neighboring gene microRNA 290a Neighboring gene microRNA 290b Neighboring gene NLR family, pyrin domain containing 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC91100, MGC91107

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables L-arginine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-lysine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-ornithine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in L-arginine import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-ornithine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cationic amino acid transporter 5
Names
cationic amino acid transporter member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004153.2 → NP_001004153.2  cationic amino acid transporter 5

    Status: VALIDATED

    Source sequence(s)
    AB201954, BC080735
    Consensus CDS
    CCDS39724.2
    UniProtKB/TrEMBL
    E9PWS4, Q0PDJ1
    Related
    ENSMUSP00000126800.2, ENSMUST00000171749.3
    Conserved Domains (2) summary
    TIGR00906
    Location:53 → 656
    2A0303; cationic amino acid transport permease
    pfam13906
    Location:604 → 654
    AA_permease_C; C-terminus of AA_permease

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    3204498..3219029 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006539984.3 → XP_006540047.1  cationic amino acid transporter 5 isoform X1

    See identical proteins and their annotated locations for XP_006540047.1

    UniProtKB/TrEMBL
    Q0PDJ1
    Related
    ENSMUST00000205185.2
    Conserved Domains (1) summary
    TIGR00906
    Location:52 → 655
    2A0303; cationic amino acid transport permease
Nucleotide Protein Strain
Heading Accession and Version

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