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Psg19 pregnancy specific glycoprotein 19 [ Rattus norvegicus (Norway rat) ]

Gene ID: 24256, updated on 18-Sep-2024

Summary

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Official Symbol
Psg19provided by RGD
Official Full Name
pregnancy specific glycoprotein 19provided by RGD
Primary source
RGD:2334
See related
EnsemblRapid:ENSRNOG00000038101 AllianceGenome:RGD:2334
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
CEAC; Cea3; Cgm3; RATCEAC
Summary
Involved in female pregnancy. Orthologous to human CEACAM21 (CEA cell adhesion molecule 21) and CEACAM4 (CEA cell adhesion molecule 4). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Psg19 in Genome Data Viewer
Location:
1q21
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (87549234..87559500, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (78421183..78431449, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (79680194..79690460, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120099773 Neighboring gene uncharacterized LOC120099774 Neighboring gene phosphoglycerate dehydrogenase, pseudogene 2 Neighboring gene carcinoembryonic antigen-related cell adhesion molecule 3-like Neighboring gene FKBP prolyl isomerase 1A, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC114333

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in T cell activation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in female pregnancy IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
carcinoembryonic antigen gene family (CGM3)
Names
pregnancy-specific glycoprotein (rnCGM3)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001270654.1 → NP_001257583.1  carcinoembryonic antigen gene family (CGM3) isoform 2 precursor

    See identical proteins and their annotated locations for NP_001257583.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    D4A4A3, Q4V8L4
    Related
    ENSRNOP00000054796.4, ENSRNOT00000057986.6
    Conserved Domains (3) summary
    cd05774
    Location:156 → 260
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
    smart00410
    Location:45 → 136
    IG_like; Immunoglobulin like
    cl11960
    Location:262 → 352
    Ig; Immunoglobulin domain

  2. NM_019126.2 → NP_061999.2  carcinoembryonic antigen gene family (CGM3) precursor

    See identical proteins and their annotated locations for NP_061999.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6J8H4, G3V9P5, Q62664
    Related
    ENSRNOP00000054798.4, ENSRNOT00000057988.7
    Conserved Domains (3) summary
    cd05774
    Location:156 → 260
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
    smart00410
    Location:45 → 136
    IG_like; Immunoglobulin like
    cl11960
    Location:382 → 472
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    87549234..87559500 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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