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CNAG_00700 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [ Cryptococcus neoformans var. grubii H99 ]

Gene ID: 23884482, updated on 17-May-2024

Summary

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Gene symbol
CNAG_00700
Gene description
phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
Locus tag
CNAG_00700
See related
FungiDB:CNAG_00700; VEuPathDB:CNAG_00700
Gene type
protein coding
RNA name
phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
RefSeq status
PROVISIONAL
Organism
Cryptococcus neoformans var. grubii H99 (strain: H99)
Lineage
Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus neoformans species complex
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Genomic context

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See CNAG_00700 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Sequence:
Chromosome: 1; NC_026745.1 (1829841..1832236)

Chromosome 1 - NC_026745.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene transmembrane receptor Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_026745.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans. Wizrah MSI, et al. J Biol Chem, 2022 Oct. PMID 36063996, Free PMC Article
  2. Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. Janbon G, et al. PLoS Genet, 2014 Apr. PMID 24743168, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans.
    Title: AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans.
Submit: New GeneRIF Correction

General gene information

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Homology

polyA_site

  • Loc: 1832100-1832100

General protein information

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Preferred Names
phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_026745.1 Reference assembly

    Range
    1829841..1832236
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012191510.1 → XP_012046900.1  phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Cryptococcus neoformans var. grubii H99]

    See identical proteins and their annotated locations for XP_012046900.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    J9VJP1
    UniProtKB/TrEMBL
    A0A225ZZG7, A0A854QL10
    Conserved Domains (2) summary
    PRK07106
    Location:216 → 605
    PRK07106; phosphoribosylaminoimidazolecarboxamide formyltransferase
    cd01421
    Location:8 → 192
    IMPCH; Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal ATIC formylase domain that formylates ...
Nucleotide Protein
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