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C2cd4c C2 calcium-dependent domain containing 4C [ Mus musculus (house mouse) ]

Gene ID: 237397, updated on 2-Nov-2024

Summary

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Official Symbol
C2cd4cprovided by MGI
Official Full Name
C2 calcium-dependent domain containing 4Cprovided by MGI
Primary source
MGI:MGI:2685084
See related
Ensembl:ENSMUSG00000045912 AllianceGenome:MGI:2685084
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm238; Fam148c; 4932409I22Rik
Summary
Is active in cytosol. Is expressed in several structures, including pancreas. Orthologous to human C2CD4C (C2 calcium dependent domain containing 4C). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in CNS E18 (RPKM 2.9), cortex adult (RPKM 1.9) and 12 other tissues See more
Orthologs
human all
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Genomic context

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See C2cd4c in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (79442688..79449859, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (79606854..79614025, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene MIER family member 2 Neighboring gene sperm microtubule associated protein 2 Neighboring gene predicted gene, 51808 Neighboring gene SHC (Src homology 2 domain containing) transforming protein 2 Neighboring gene CIMAP1 family member D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. our results suggest that C2cd4c is dispensable for pancreatic development.
    Title: Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC86088

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
C2 calcium-dependent domain-containing protein 4C
Names
C2cd4cC2CD4 family
family with sequence similarity 148, member C
nuclear-localized factor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168624.1 → NP_001162095.1  C2 calcium-dependent domain-containing protein 4C

    See identical proteins and their annotated locations for NP_001162095.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AK029946, BC089008
    Consensus CDS
    CCDS23979.1
    UniProtKB/Swiss-Prot
    Q5HZI2, Q8CDK0
    Related
    ENSMUSP00000136013.2, ENSMUST00000178228.3
    Conserved Domains (1) summary
    smart00239
    Location:319 → 416
    C2; Protein kinase C conserved region 2 (CalB)

  2. NM_198614.3 → NP_941016.2  C2 calcium-dependent domain-containing protein 4C

    See identical proteins and their annotated locations for NP_941016.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    BC089008, BY268666
    Consensus CDS
    CCDS23979.1
    UniProtKB/Swiss-Prot
    Q5HZI2, Q8CDK0
    Related
    ENSMUSP00000059433.8, ENSMUST00000059699.9
    Conserved Domains (1) summary
    smart00239
    Location:319 → 416
    C2; Protein kinase C conserved region 2 (CalB)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    79442688..79449859 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5HZI2.1 GenPept UniProtKB/Swiss-Prot:Q5HZI2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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