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Mrgpra4 MAS-related GPR, member A4 [ Mus musculus (house mouse) ]

Gene ID: 235854, updated on 2-Nov-2024

Summary

Official Symbol
Mrgpra4provided by MGI
Official Full Name
MAS-related GPR, member A4provided by MGI
Primary source
MGI:MGI:3033100
See related
Ensembl:ENSMUSG00000067173 AllianceGenome:MGI:3033100
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MrgA4; Mgrg10
Summary
Enables neuropeptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human MRGPRX4 (MAS related GPR family member X4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See Mrgpra4 in Genome Data Viewer
Location:
7 B4; 7 31.08 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (47630542..47632044, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (47980794..47982296, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene MAS-related GPR, member A4 pseudogene Neighboring gene MAS-related GPR, member C2, pseudogene Neighboring gene MAS-related GPR, member X1 Neighboring gene MAS-related GPR, member B7, pseudogene

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables neuropeptide receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mas-related G-protein coupled receptor member A4
Names
Mas-related G protein-coupled receptor g10
MrgA4 RF-amide G protein-coupled receptor
RF-amide G-protein coupled receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153524.2NP_705744.2  mas-related G-protein coupled receptor member A4

    See identical proteins and their annotated locations for NP_705744.2

    Status: VALIDATED

    Source sequence(s)
    AY042194, BC115741
    Consensus CDS
    CCDS21298.1
    UniProtKB/Swiss-Prot
    Q1RLL1, Q91WW2
    UniProtKB/TrEMBL
    B7ZP12, W8W3F5
    Related
    ENSMUSP00000084327.3, ENSMUST00000087092.4
    Conserved Domains (1) summary
    pfam00001
    Location:38270
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    47630542..47632044 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)