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Ino80e INO80 complex subunit E [ Mus musculus (house mouse) ]

Gene ID: 233875, updated on 2-Nov-2024

Summary

Official Symbol
Ino80eprovided by MGI
Official Full Name
INO80 complex subunit Eprovided by MGI
Primary source
MGI:MGI:2141881
See related
Ensembl:ENSMUSG00000030689 AllianceGenome:MGI:2141881
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ccdc85; Ccdc95
Summary
Predicted to be involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Ino80 complex. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human INO80E (INO80 complex subunit E). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in thymus adult (RPKM 20.5), ovary adult (RPKM 17.3) and 28 other tissues See more
Orthologs
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Genomic context

See Ino80e in Genome Data Viewer
Location:
7 F3; 7 69.25 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126450756..126461544, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (126851584..126862372, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene TLC domain containing 3B Neighboring gene RIKEN cDNA 4930451I11 gene Neighboring gene double C2, alpha Neighboring gene STARR-positive B cell enhancer ABC_E8843 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134005673-134005856 Neighboring gene HIRA interacting protein 3 Neighboring gene TAO kinase 2 Neighboring gene STARR-positive B cell enhancer ABC_E2849 Neighboring gene transmembrane protein 219 Neighboring gene predicted gene, 23445

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC31515

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in chromatin remodeling ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of DNA replication ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of DNA strand elongation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of chromosome organization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of Ino80 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Ino80 complex ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
INO80 complex subunit E
Names
NO80 complex subunit E
coiled-coil domain containing 95

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370765.1NP_001357694.1  INO80 complex subunit E isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC124505
    Related
    ENSMUST00000125624.8
  2. NM_153580.1NP_705808.1  INO80 complex subunit E isoform 2

    See identical proteins and their annotated locations for NP_705808.1

    Status: VALIDATED

    Source sequence(s)
    BC026475
    Consensus CDS
    CCDS21848.1
    UniProtKB/TrEMBL
    Q8R359
    Related
    ENSMUSP00000049851.8, ENSMUST00000050833.14

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    126450756..126461544 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507733.4XP_006507796.1  INO80 complex subunit E isoform X7

  2. XM_036153016.1XP_036008909.1  INO80 complex subunit E isoform X6

  3. XM_011241778.3XP_011240080.1  INO80 complex subunit E isoform X5

    See identical proteins and their annotated locations for XP_011240080.1

    Conserved Domains (1) summary
    pfam08537
    Location:77161
    NBP1; Fungal Nap binding protein NBP1
  4. XM_006507731.1XP_006507794.1  INO80 complex subunit E isoform X2

    UniProtKB/TrEMBL
    A0A0U1RP99
    Related
    ENSMUSP00000145893.2, ENSMUST00000206968.2
    Conserved Domains (1) summary
    pfam08537
    Location:77161
    NBP1; Fungal Nap binding protein NBP1
  5. XM_006507730.1XP_006507793.1  INO80 complex subunit E isoform X1

    UniProtKB/TrEMBL
    A0A0U1RP99
  6. XM_011241777.3XP_011240079.1  INO80 complex subunit E isoform X4

    UniProtKB/TrEMBL
    A0A0U1RP99
  7. XM_006507732.3XP_006507795.1  INO80 complex subunit E isoform X3

    See identical proteins and their annotated locations for XP_006507795.1

RNA

  1. XR_378240.4 RNA Sequence

    Related
    ENSMUST00000106343.3
  2. XR_003946467.1 RNA Sequence

  3. XR_003946466.1 RNA Sequence

  4. XR_378241.5 RNA Sequence

  5. XR_378239.1 RNA Sequence