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Gdpd4 glycerophosphodiester phosphodiesterase domain containing 4 [ Mus musculus (house mouse) ]

Gene ID: 233537, updated on 28-Oct-2024

Summary

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Official Symbol
Gdpd4provided by MGI
Official Full Name
glycerophosphodiester phosphodiesterase domain containing 4provided by MGI
Primary source
MGI:MGI:3606573
See related
Ensembl:ENSMUSG00000035582 AllianceGenome:MGI:3606573
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4921513O04
Summary
Predicted to enable glycerophosphodiester phosphodiesterase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in cytoplasm. Predicted to be active in membrane. Orthologous to human GDPD4 (glycerophosphodiester phosphodiesterase domain containing 4). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Restricted expression toward testis adult (RPKM 4.6) See more
Orthologs
human all
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Genomic context

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See Gdpd4 in Genome Data Viewer
Location:
7 E1; 7 53.57 cM
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (97569151..97698870)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (97919944..98049663)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:104879154-104879355 Neighboring gene STARR-seq mESC enhancer starr_19606 Neighboring gene STARR-seq mESC enhancer starr_19609 Neighboring gene aquaporin 11 Neighboring gene p21 (RAC1) activated kinase 1 Neighboring gene STARR-seq mESC enhancer starr_19614 Neighboring gene STARR-seq mESC enhancer starr_19615 Neighboring gene ubiquinol-cytochrome c reductase complex chaperone, CBP3 homolog pseudogene Neighboring gene myosin VIIA Neighboring gene STARR-seq mESC enhancer starr_19616 Neighboring gene STARR-positive B cell enhancer mm9_chr7:105268750-105269051 Neighboring gene calpain 5 Neighboring gene olfactory marker protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Isolation and characterization of two serpentine membrane proteins containing glycerophosphodiester phosphodiesterase, GDE2 and GDE6. Nogusa Y, et al. Gene, 2004 Aug 4. PMID 15276213
  2. Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice. Fujihara Y, et al. Proc Natl Acad Sci U S A, 2019 Sep 10. PMID 31455729, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables glycerophosphodiester phosphodiesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables phosphoric diester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glycerophosphodiester phosphodiesterase domain-containing protein 4
Names
glycerophosphodiester phosphodiesterase 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177696.3 → NP_808364.2  glycerophosphodiester phosphodiesterase domain-containing protein 4

    See identical proteins and their annotated locations for NP_808364.2

    Status: VALIDATED

    Source sequence(s)
    AK029527, AK161500
    Consensus CDS
    CCDS52318.1
    UniProtKB/Swiss-Prot
    Q3TT99, Q8BI25
    UniProtKB/TrEMBL
    B2RU67
    Related
    ENSMUSP00000036772.7, ENSMUST00000041860.13
    Conserved Domains (2) summary
    pfam03009
    Location:281 → 528
    GDPD; Glycerophosphoryl diester phosphodiesterase family
    cl14615
    Location:254 → 567
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    97569151..97698870
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507611.1 → XP_006507674.1  glycerophosphodiester phosphodiesterase domain-containing protein 4 isoform X1

    Conserved Domains (1) summary
    cl14615
    Location:254 → 567
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily

  2. XM_006507612.2 → XP_006507675.1  glycerophosphodiester phosphodiesterase domain-containing protein 4 isoform X2

    See identical proteins and their annotated locations for XP_006507675.1

    Conserved Domains (1) summary
    cl14615
    Location:187 → 500
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily

  3. XM_006507613.3 → XP_006507676.1  glycerophosphodiester phosphodiesterase domain-containing protein 4 isoform X2

    See identical proteins and their annotated locations for XP_006507676.1

    Conserved Domains (1) summary
    cl14615
    Location:187 → 500
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily

  4. XM_006507614.1 → XP_006507677.1  glycerophosphodiester phosphodiesterase domain-containing protein 4 isoform X3

    Conserved Domains (1) summary
    cl14615
    Location:36 → 349
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3TT99.1 GenPept UniProtKB/Swiss-Prot:Q3TT99

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