U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Scgb2b27 secretoglobin, family 2B, member 27 [ Mus musculus (house mouse) ]

Gene ID: 233099, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
Scgb2b27provided by MGI
Official Full Name
secretoglobin, family 2B, member 27provided by MGI
Primary source
MGI:MGI:87863
See related
Ensembl:ENSMUSG00000066584 AllianceGenome:MGI:87863
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Abpbg5; Abpbg27; Scgb2b5
Summary
Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Scgb2b27 in Genome Data Viewer
Location:
7 B1; 7 19.38 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (33711344..33713367, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (34011919..34013942, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 329 pseudogene Neighboring gene predicted gene 12755 Neighboring gene STARR-seq mESC enhancer starr_18574 Neighboring gene secretoglobin, family 1B, member 27 Neighboring gene STARR-seq mESC enhancer starr_18576 Neighboring gene 60S ribosomal protein L21-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Studies of an Androgen-Binding Protein Knockout Corroborate a Role for Salivary ABP in Mouse Communication. Chung AG, et al. Genetics, 2017 Apr. PMID 28159752, Free PMC Article
  2. The amino acid sequence of the alpha subunit of mouse salivary androgen-binding protein (ABP), with a comparison to the partial sequence of the beta subunit and to other ligand-binding proteins. Karn RC, et al. Biochem Genet, 1993 Aug. PMID 8274137
  3. Congenic strain analysis reveals genes that are rapidly evolving components of a prezygotic isolation mechanism mediating incipient reinforcement. Laukaitis CM, et al. PLoS One, 2012. PMID 22558260, Free PMC Article
  4. The microevolution of mouse salivary androgen-binding protein (ABP) paralleled subspeciation of Mus musculus. Hwang JM, et al. J Hered, 1997 Mar-Apr. PMID 9099004
  5. Characterization of two forms of mouse salivary androgen-binding protein (ABP): implications for evolutionary relationships and ligand-binding function. Karn RC, et al. Biochemistry, 2003 Jun 17. PMID 12795612

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ABP subunit BG27 shares phylogenetic relationships with Fel d 1 chains.
    Title: Another cat and mouse game: Deciphering the evolution of the SCGB superfamily and exploring the molecular similarity of major cat allergen Fel d 1 and mouse ABP using computational approaches.
Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC19070, MGC156367

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in extracellular region TAS
Traceable Author Statement
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
secretoglobin, family 2B, member 27
Names
allergen dI chain C2A
androgen binding protein beta
secretoglobin, family 2B, member 5

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100464.2 → NP_001093934.1  secretoglobin, family 2B, member 27 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001093934.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    BK000193, BX539309
    Consensus CDS
    CCDS52200.1
    UniProtKB/TrEMBL
    A0A7H1MFN9, A0A7S8WJW3, Q7TNY5, Q8R1E9
    Related
    ENSMUSP00000082760.3, ENSMUST00000085620.9
    Conserved Domains (1) summary
    pfam09252
    Location:24 → 90
    Feld-I_B; Allergen Fel d I-B chain

  2. NM_001276475.1 → NP_001263404.1  secretoglobin, family 2B, member 27 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001263404.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    BK000193, BX539309
    Consensus CDS
    CCDS80703.1
    UniProtKB/TrEMBL
    A0A087WRN7
    Related
    ENSMUSP00000140711.2, ENSMUST00000185399.2
    Conserved Domains (1) summary
    pfam09252
    Location:24 → 82
    Feld-I_B; Allergen Fel d I-B chain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    33711344..33713367 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools