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ANKRD28 ankyrin repeat domain 28 [ Homo sapiens (human) ]

Gene ID: 23243, updated on 3-Nov-2024

Summary

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Official Symbol
ANKRD28provided by HGNC
Official Full Name
ankyrin repeat domain 28provided by HGNC
Primary source
HGNC:HGNC:29024
See related
Ensembl:ENSG00000206560 MIM:611122; AllianceGenome:HGNC:29024
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PITK; FAP79; CFAP79; PPP1R65
Summary
Predicted to be located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in bone marrow (RPKM 14.3), testis (RPKM 10.7) and 25 other tissues See more
Orthologs
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Genomic context

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See ANKRD28 in Genome Data Viewer
Location:
3p25.1
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (15667236..15859814, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (15669546..15862982, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (15708743..15901321, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene collagen like tail subunit of asymmetric acetylcholinesterase Neighboring gene RNA, 7SL, cytoplasmic 110, pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:15642981-15643623 Neighboring gene 2-hydroxyacyl-CoA lyase 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:15688189-15688722 Neighboring gene Sharpr-MPRA regulatory region 6531 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_65637 Neighboring gene biotinidase Neighboring gene microRNA 3134 Neighboring gene uncharacterized LOC101927647 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14108 Neighboring gene RNA, 7SL, cytoplasmic 4, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19535 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14109 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19536 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19537 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19538 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:15887901-15888400 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14110 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14111 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14112 Neighboring gene uncharacterized LOC107986064 Neighboring gene inosine monophosphate dehydrogenase 1 pseudogene 8 Neighboring gene microRNA 563

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. [Effect of hnRNP K and its interaction with HPV16 on cervical intraepithelial neoplasia]. Ding L, et al. Zhonghua Liu Xing Bing Xue Za Zhi, 2018 Dec 10. PMID 30572391
  2. circANKRD28 inhibits cisplatin resistance in non-small-cell lung cancer through the miR-221-3p/SOCS3 axis. Song S, et al. J Gene Med, 2023 Apr. PMID 36740786
  3. Dual kinase-mediated regulation of PITK by CaMKII and GSK3. Kwiek NC, et al. Cell Signal, 2007 Mar. PMID 17023142
  4. Regulation of focal adhesion and cell migration by ANKRD28-DOCK180 interaction. Kiyokawa E, et al. Cell Adh Migr, 2009 Jul-Sep. PMID 19458477, Free PMC Article
  5. Epidermal growth factor increases the interaction between nucleolin and heterogeneous nuclear ribonucleoprotein K/poly(C) binding protein 1 complex to regulate the gastrin mRNA turnover. Lee PT, et al. Mol Biol Cell, 2007 Dec. PMID 17928403, Free PMC Article

See all (99) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. circANKRD28 inhibits cisplatin resistance in non-small-cell lung cancer through the miR-221-3p/SOCS3 axis.
    Title: circANKRD28 inhibits cisplatin resistance in non-small-cell lung cancer through the miR-221-3p/SOCS3 axis.
  2. HPV16 infection and over-expression of hnRNP K protein were associated with the increased risk of cervical intraepithelial neoplasia. There might be interaction between hnRNP K protein overexpression and HPV16 infection existed on the progress of CIN/ [ cervical intraepithelial neoplasia II/III].
    Title: [Effect of hnRNP K and its interaction with HPV16 on cervical intraepithelial neoplasia].
  3. findings suggest that BRCA1 is a novel modulator of PP6 signalling via its interaction with ANKRD28.
    Title: BRCA1 affects protein phosphatase 6 signalling through its interaction with ANKRD28.
  4. hnRNP K and hnRNP L may serve as A1CF-like cofactors in AID-mediated class switch recombination and somatic hypermutation
    Title: Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase.
  5. ANKRD28, a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation.
    Title: Ankyrin repeat domain 28 (ANKRD28), a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation.
  6. CaMKII and GSK3 mediate regulation of PITK.
    Title: Dual kinase-mediated regulation of PITK by CaMKII and GSK3.
  7. These findings provide a putative mechanism by which transcriptional activity of hnRNP K can be discretely controlled through the regulation of PP1 activity.
    Title: PITK, a PP1 targeting subunit that modulates the phosphorylation of the transcriptional regulator hnRNP K.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA0379

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
Names
PP6-ARS-A
ankyrin repeat domain-containing protein 28
phosphatase interactor targeting K protein
phosphatase interactor targeting protein hnRNP K
protein phosphatase 1, regulatory subunit 65
protein phosphatase 6 ankyrin repeat subunit A
serine/threonine-protein phosphatase 6 regulatory subunit ARS-A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195098.1 → NP_001182027.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform b

    See identical proteins and their annotated locations for NP_001182027.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variants 3 and 10, encodes isoform b.
    Source sequence(s)
    AC090950, AK293770, AY367056, BQ423818
    Consensus CDS
    CCDS74908.1
    UniProtKB/Swiss-Prot
    O15084
    Related
    ENSP00000485421.1, ENST00000624145.3
    Conserved Domains (6) summary
    PHA02874
    Location:400 → 709
    PHA02874; ankyrin repeat protein; Provisional
    PHA03095
    Location:65 → 321
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:22 → 49
    ANK; ANK repeat [structural motif]
    pfam00023
    Location:773 → 803
    Ank; Ankyrin repeat
    pfam12796
    Location:673 → 766
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:1 → 116
    Ank_2; Ankyrin repeats (3 copies)

  2. NM_001195099.2 → NP_001182028.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform b

    See identical proteins and their annotated locations for NP_001182028.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3), as well as variants 2 and 10, encodes isoform b.
    Source sequence(s)
    AC090950, AK293770, AY367056, BQ423818
    Consensus CDS
    CCDS74908.1
    UniProtKB/Swiss-Prot
    O15084
    Conserved Domains (6) summary
    PHA02874
    Location:400 → 709
    PHA02874; ankyrin repeat protein; Provisional
    PHA03095
    Location:65 → 321
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:22 → 49
    ANK; ANK repeat [structural motif]
    pfam00023
    Location:773 → 803
    Ank; Ankyrin repeat
    pfam12796
    Location:673 → 766
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:1 → 116
    Ank_2; Ankyrin repeats (3 copies)

  3. NM_001349277.2 → NP_001336206.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) encodes isoform c.
    Source sequence(s)
    AC090950
    Conserved Domains (5) summary
    PHA02874
    Location:587 → 896
    PHA02874; ankyrin repeat protein; Provisional
    PHA03095
    Location:55 → 343
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:173 → 203
    ANK; ANK repeat [structural motif]
    pfam00023
    Location:960 → 990
    Ank; Ankyrin repeat
    pfam12796
    Location:860 → 953
    Ank_2; Ankyrin repeats (3 copies)

  4. NM_001349278.2 → NP_001336207.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) encodes isoform d.
    Source sequence(s)
    AC090950
    Consensus CDS
    CCDS93222.1
    Related
    ENSP00000508086.1, ENST00000683139.1
    Conserved Domains (5) summary
    PHA02874
    Location:584 → 893
    PHA02874; ankyrin repeat protein; Provisional
    PHA03095
    Location:52 → 340
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:170 → 200
    ANK; ANK repeat [structural motif]
    pfam00023
    Location:957 → 987
    Ank; Ankyrin repeat
    pfam12796
    Location:857 → 950
    Ank_2; Ankyrin repeats (3 copies)

  5. NM_001349279.2 → NP_001336208.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform e

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) encodes isoform e.
    Source sequence(s)
    AC090945, AC090950
    Conserved Domains (5) summary
    PHA02874
    Location:551 → 860
    PHA02874; ankyrin repeat protein; Provisional
    PHA03095
    Location:19 → 307
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:137 → 167
    ANK; ANK repeat [structural motif]
    pfam00023
    Location:924 → 954
    Ank; Ankyrin repeat
    pfam12796
    Location:824 → 917
    Ank_2; Ankyrin repeats (3 copies)

  6. NM_001349280.1 → NP_001336209.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform f

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variants 8 and 9, encodes isoform f.
    Source sequence(s)
    AC090950
    Conserved Domains (5) summary
    cd00204
    Location:78 → 203
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:84 → 114
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:319 → 360
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:483 → 534
    Ank_5; Ankyrin repeats (many copies)
    cl26073
    Location:30 → 303
    Ank_2; Ankyrin repeats (3 copies)

  7. NM_001349281.2 → NP_001336210.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform f

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8), as well as variants 7 and 9, encodes isoform f.
    Source sequence(s)
    AC090950
    Conserved Domains (5) summary
    cd00204
    Location:78 → 203
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:84 → 114
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:319 → 360
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:483 → 534
    Ank_5; Ankyrin repeats (many copies)
    cl26073
    Location:30 → 303
    Ank_2; Ankyrin repeats (3 copies)

  8. NM_001349282.2 → NP_001336211.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform f

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9), as well as variants 7 and 8, encodes isoform f.
    Source sequence(s)
    AC090950
    Conserved Domains (5) summary
    cd00204
    Location:78 → 203
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:84 → 114
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:319 → 360
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:483 → 534
    Ank_5; Ankyrin repeats (many copies)
    cl26073
    Location:30 → 303
    Ank_2; Ankyrin repeats (3 copies)

  9. NM_001349283.2 → NP_001336212.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10), as well as variants 2 and 3, encodes isoform b.
    Source sequence(s)
    AC090950
    Consensus CDS
    CCDS74908.1
    Conserved Domains (6) summary
    PHA02874
    Location:400 → 709
    PHA02874; ankyrin repeat protein; Provisional
    PHA03095
    Location:65 → 321
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:22 → 49
    ANK; ANK repeat [structural motif]
    pfam00023
    Location:773 → 803
    Ank; Ankyrin repeat
    pfam12796
    Location:673 → 766
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:1 → 116
    Ank_2; Ankyrin repeats (3 copies)

  10. NM_001349284.2 → NP_001336213.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) encodes isoform g.
    Source sequence(s)
    AC090950

  11. NM_001349285.2 → NP_001336214.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform h

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12) encodes isoform h.
    Source sequence(s)
    AC090950
    Related
    ENST00000461696.1

  12. NM_015199.4 → NP_056014.2  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform a

    See identical proteins and their annotated locations for NP_056014.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform a.
    Source sequence(s)
    AC090945, AC090950, AI565587, AK293770, AY367056, BQ423818, CN313636
    Consensus CDS
    CCDS46769.1
    UniProtKB/Swiss-Prot
    B4DES5, O15084, Q1WWL4, Q29RW6, Q3B857, Q6ULS0, Q6ZT57
    Related
    ENSP00000382379.2, ENST00000399451.6
    Conserved Domains (5) summary
    PHA02874
    Location:554 → 863
    PHA02874; ankyrin repeat protein; Provisional
    PHA03095
    Location:22 → 310
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:140 → 170
    ANK; ANK repeat [structural motif]
    pfam00023
    Location:927 → 957
    Ank; Ankyrin repeat
    pfam12796
    Location:827 → 920
    Ank_2; Ankyrin repeats (3 copies)

RNA

  1. NR_146111.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC090950

  2. NR_146112.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC090950

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    15667236..15859814 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047447807.1 → XP_047303763.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X10

  2. XM_011533542.4 → XP_011531844.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X4

    See identical proteins and their annotated locations for XP_011531844.1

    Conserved Domains (6) summary
    cd00204
    Location:619 → 748
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:112 → 142
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:414 → 498
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:900 → 951
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:511 → 562
    Ank_5; Ankyrin repeats (many copies)
    cl26073
    Location:6 → 273
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_024453422.2 → XP_024309190.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

    Conserved Domains (5) summary
    cd00204
    Location:78 → 203
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:84 → 114
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:319 → 360
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:483 → 534
    Ank_5; Ankyrin repeats (many copies)
    cl26073
    Location:30 → 303
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_047447809.1 → XP_047303765.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X12

  5. XM_047447810.1 → XP_047303766.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X13

  6. XM_024453419.2 → XP_024309187.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X2

    Conserved Domains (6) summary
    cd00204
    Location:658 → 787
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:151 → 181
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:453 → 537
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:939 → 990
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:550 → 601
    Ank_5; Ankyrin repeats (many copies)
    cl26073
    Location:33 → 321
    Ank_2; Ankyrin repeats (3 copies)

  7. XM_024453418.2 → XP_024309186.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1

    Conserved Domains (6) summary
    cd00204
    Location:661 → 790
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:154 → 184
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:456 → 540
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:942 → 993
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:553 → 604
    Ank_5; Ankyrin repeats (many copies)
    cl26073
    Location:36 → 324
    Ank_2; Ankyrin repeats (3 copies)

  8. XM_024453424.2 → XP_024309192.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

    Conserved Domains (5) summary
    cd00204
    Location:78 → 203
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:84 → 114
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:319 → 360
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:483 → 534
    Ank_5; Ankyrin repeats (many copies)
    cl26073
    Location:30 → 303
    Ank_2; Ankyrin repeats (3 copies)

  9. XM_047447805.1 → XP_047303761.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

  10. XM_047447804.1 → XP_047303760.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

  11. XM_011533547.4 → XP_011531849.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

    See identical proteins and their annotated locations for XP_011531849.1

    Conserved Domains (5) summary
    cd00204
    Location:78 → 203
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:84 → 114
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:319 → 360
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:483 → 534
    Ank_5; Ankyrin repeats (many copies)
    cl26073
    Location:30 → 303
    Ank_2; Ankyrin repeats (3 copies)

  12. XM_047447803.1 → XP_047303759.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X7

  13. XM_047447802.1 → XP_047303758.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X6

  14. XM_047447813.1 → XP_047303769.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X16

  15. XM_047447806.1 → XP_047303762.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X9

  16. XM_047447808.1 → XP_047303764.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X11

  17. XM_047447801.1 → XP_047303757.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X5

  18. XM_047447800.1 → XP_047303756.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X3

  19. XM_047447811.1 → XP_047303767.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X14

  20. XM_047447812.1 → XP_047303768.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X15

RNA

  1. XR_007095653.1 RNA Sequence

  2. XR_007095652.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    15669546..15862982 complement
    Download
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mRNA and Protein(s)

  1. XM_054345869.1 → XP_054201844.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X10

  2. XM_054345859.1 → XP_054201834.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X4

  3. XM_054345867.1 → XP_054201842.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

  4. XM_054345871.1 → XP_054201846.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X12

  5. XM_054345872.1 → XP_054201847.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X13

  6. XM_054345857.1 → XP_054201832.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X2

  7. XM_054345856.1 → XP_054201831.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1

  8. XM_054345865.1 → XP_054201840.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

  9. XM_054345864.1 → XP_054201839.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

  10. XM_054345863.1 → XP_054201838.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

  11. XM_054345866.1 → XP_054201841.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

  12. XM_054345862.1 → XP_054201837.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X7

  13. XM_054345861.1 → XP_054201836.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X6

  14. XM_054345875.1 → XP_054201850.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X16

  15. XM_054345868.1 → XP_054201843.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X9

  16. XM_054345870.1 → XP_054201845.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X11

  17. XM_054345860.1 → XP_054201835.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X5

  18. XM_054345858.1 → XP_054201833.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X3

  19. XM_054345873.1 → XP_054201848.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X14

  20. XM_054345874.1 → XP_054201849.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X15

RNA

  1. XR_008486682.1 RNA Sequence

  2. XR_008486681.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O15084.5 GenPept UniProtKB/Swiss-Prot:O15084

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