U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Gm572 predicted gene 572 [ Mus musculus (house mouse) ]

Gene ID: 230909, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Gm572provided by MGI
Official Full Name
predicted gene 572provided by MGI
Primary source
MGI:MGI:2685418
See related
Ensembl:ENSMUSG00000070577 AllianceGenome:MGI:2685418
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
b2b1167Clo
Summary
Acts upstream of or within determination of left/right symmetry and heart development. Is expressed in several structures, including alimentary system; genitourinary system; and trachea. Used to study Kartagener syndrome; primary ciliary dyskinesia; and visceral heterotaxy. Orthologous to human C1orf127 (chromosome 1 open reading frame 127). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in stomach adult (RPKM 5.0), heart adult (RPKM 5.0) and 3 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Gm572 in Genome Data Viewer
Location:
4 E2; 4 78.82 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (148727774..148761562)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (148643317..148677105)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene MBL associated serine protease 2 Neighboring gene spermidine synthase Neighboring gene TAR DNA binding protein Neighboring gene STARR-positive B cell enhancer ABC_E4729 Neighboring gene STARR-seq mESC enhancer starr_12080 Neighboring gene STARR-seq mESC enhancer starr_12082 Neighboring gene STARR-seq mESC enhancer starr_12083 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:148057732-148057915 Neighboring gene predicted gene 13203 Neighboring gene STARR-seq mESC enhancer starr_12087 Neighboring gene STARR-seq mESC enhancer starr_12089 Neighboring gene predicted gene, 32897

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J. Timmermans S, et al. JCI Insight, 2018 Jul 12. PMID 29997285, Free PMC Article
  2. Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Li Y, et al. Nature, 2015 May 28. PMID 25807483, Free PMC Article
  3. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
  4. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Chemically induced (ENU) (1) 
  • Targeted (4) 

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within determination of left/right symmetry IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within heart development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein C1orf127 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085505.1 → NP_001078974.1  uncharacterized protein C1orf127 homolog isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL606969
    Consensus CDS
    CCDS51378.1
    UniProtKB/TrEMBL
    B1ARY8
    Related
    ENSMUSP00000101323.3, ENSMUST00000105698.3
    Conserved Domains (1) summary
    pfam15094
    Location:144 → 358
    DUF4556; Domain of unknown function (DUF4556)

  2. NM_001368835.1 → NP_001355764.1  uncharacterized protein C1orf127 homolog isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AL606969
    Related
    ENSMUSP00000160098.1, ENSMUST00000250014.1
    Conserved Domains (2) summary
    PHA03247
    Location:370 → 767
    PHA03247; large tegument protein UL36; Provisional
    pfam15094
    Location:144 → 358
    DUF4556; Domain of unknown function (DUF4556)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    148727774..148761562
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164087.1 → XP_036019980.1  uncharacterized protein C1orf127 homolog isoform X3

    Conserved Domains (1) summary
    pfam15094
    Location:144 → 358
    DUF4556; Domain of unknown function (DUF4556)

  2. XM_036164088.1 → XP_036019981.1  uncharacterized protein C1orf127 homolog isoform X4

    Conserved Domains (1) summary
    pfam15094
    Location:144 → 358
    DUF4556; Domain of unknown function (DUF4556)

  3. XM_006538816.3 → XP_006538879.1  uncharacterized protein C1orf127 homolog isoform X1

    Conserved Domains (2) summary
    PHA03247
    Location:324 → 721
    PHA03247; large tegument protein UL36; Provisional
    pfam15094
    Location:144 → 312
    DUF4556; Domain of unknown function (DUF4556)

  4. XM_006538818.2 → XP_006538881.1  uncharacterized protein C1orf127 homolog isoform X2

    Conserved Domains (2) summary
    PHA03247
    Location:150 → 475
    PHA03247; large tegument protein UL36; Provisional
    pfam15094
    Location:2 → 138
    DUF4556; Domain of unknown function (DUF4556)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials