ERC1 - ELKS/RAB6-interacting/CAST family member 1
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
NCBI Orthologs
How was this calculated?genes for:
Protein alignment
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Species | Gene | Architecture | aa |
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