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RIMS1 regulating synaptic membrane exocytosis 1 [ Homo sapiens (human) ]

Gene ID: 22999, updated on 7-Apr-2024

Summary

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Official Symbol
RIMS1provided by HGNC
Official Full Name
regulating synaptic membrane exocytosis 1provided by HGNC
Primary source
HGNC:HGNC:17282
See related
Ensembl:ENSG00000079841 MIM:606629; AllianceGenome:HGNC:17282
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RIM; RIM1; CORD7; RAB3IP2
Summary
The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
Expression
Biased expression in brain (RPKM 5.2), testis (RPKM 1.0) and 4 other tissues See more
Orthologs
mouse all
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Genomic context

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See RIMS1 in Genome Data Viewer
Location:
6q13
Exon count:
42
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (71886550..72403145)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (73067717..73580721)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (72596253..73112847)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_94343 Neighboring gene keratin 19 pseudogene 1 Neighboring gene RNA, U4 small nuclear 66, pseudogene Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:72478705-72479904 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:72541212-72542010 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:72542011-72542808 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17327 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17328 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24736 Neighboring gene forkhead box H1 pseudogene Neighboring gene uncharacterized LOC107986611 Neighboring gene MPRA-validated peak5889 silencer Neighboring gene MPRA-validated peak5890 silencer Neighboring gene DNA polymerase delta 1, catalytic subunit pseudogene Neighboring gene HORMA domain containing 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Retinitis pigmentosa and bilateral cystoid macular oedema in a patient heterozygous for the RIM1 mutation previously associated with cone-rod dystrophy 7. Warwick AN, et al. Ophthalmic Genet, 2017 Mar-Apr. PMID 27176872
  2. Functional coupling of Rab3-interacting molecule 1 (RIM1) and L-type Ca2+ channels in insulin release. Gandini MA, et al. J Biol Chem, 2011 May 6. PMID 21402706, Free PMC Article
  3. Rim1 modulates direct G-protein regulation of Ca(v)2.2 channels. Weiss N, et al. Pflugers Arch, 2011 Apr. PMID 21331761, Free PMC Article
  4. Molecular analysis of RIM1 in autosomal recessive Retinitis pigmentosa. Barragan I, et al. Ophthalmic Res, 2005 Mar-Apr. PMID 15746564
  5. Genomic organisation and alternative splicing of human RIM1, a gene implicated in autosomal dominant cone-rod dystrophy (CORD7). Johnson S, et al. Genomics, 2003 Mar. PMID 12659814

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This is the first reported case of bilateral cystoid macular edema in association with the RIM1 mutation. Overall, our findings were more consistent with a phenotype of retinitis pigmentosa.
    Title: Retinitis pigmentosa and bilateral cystoid macular oedema in a patient heterozygous for the RIM1 mutation previously associated with cone-rod dystrophy 7.
  2. The study identified a region on chromosome 6 comprising the genes SMAP1, B3GAT2, and RIMS1 as novel susceptibility locus for pediatric venous thromboembolism.
    Title: Rare genetic variants in SMAP1, B3GAT2, and RIMS1 contribute to pediatric venous thromboembolism.
  3. Electrophysiological characterization of VDCC currents revealed that the suppressive effect of RIM2alpha on voltage-dependent inactivation (VDI) was stronger than that of RIM1alpha for the CaV2.1 variant containing the region encoded by exons 44 and 47.
    Title: C-terminal splice variants of P/Q-type Ca(2+) channel Ca(V)2.1 α(1) subunits are differentially regulated by Rab3-interacting molecule proteins.
  4. Here, we report that, like Rab3A, RIM and Munc13 are present in human sperm and that they play a functional role in acrosomal exocytosis before the acrosomal calcium efflux
    Title: RIM, Munc13, and Rab3A interplay in acrosomal exocytosis.
  5. a novel functional coupling between RIM1 and the L-type Ca(V) channels via the Ca(V)beta auxiliary subunit that contribute to determine insulin secretion.
    Title: Functional coupling of Rab3-interacting molecule 1 (RIM1) and L-type Ca2+ channels in insulin release.
  6. Rim1 modulates direct G-protein regulation of Ca(v)2.2 channels.
    Title: Rim1 modulates direct G-protein regulation of Ca(v)2.2 channels.
  7. Observational study of genetic testing. (HuGE Navigator)
    Title: Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip.
  8. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
  9. Observational study of gene-disease association. (HuGE Navigator)
    Title: Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.
  10. Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
    Title: Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.
Submit: New GeneRIF Correction See all GeneRIFs (13)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Copy number response

Description
Copy number response
Triplosensitivity

No evidence available (Last evaluated 2018-01-24)

ClinGen Genome Curation Page
Haploinsufficency

Little evidence for dosage pathogenicity (Last evaluated 2018-01-24)

ClinGen Genome Curation PagePubMed

EBI GWAS Catalog

Description
Biological insights from 108 schizophrenia-associated genetic loci.
EBI GWAS Catalog
Common genetic variation and performance on standardized cognitive tests.
EBI GWAS Catalog
Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system.
EBI GWAS Catalog
Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA0340, MGC167823, MGC176677

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GTPase regulator activity TAS
Traceable Author Statement
more info
 PubMed 
enables RNA binding HDA PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables small GTPase binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transmembrane transporter binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in acrosomal vesicle exocytosis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in calcium ion-regulated exocytosis of neurotransmitter IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in calcium-ion regulated exocytosis TAS
Traceable Author Statement
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in membrane fusion NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in positive regulation of dendrite extension IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of excitatory postsynaptic potential ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of gene expression ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of inhibitory postsynaptic potential ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein-containing complex assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulated exocytosis NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of membrane potential IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of neurotransmitter secretion TAS
Traceable Author Statement
more info
 PubMed 
involved_in regulation of synaptic plasticity IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of synaptic vesicle exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to stimulus IEA
Inferred from Electronic Annotation
more info
  
involved_in secretion NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in synaptic vesicle exocytosis TAS
Traceable Author Statement
more info
 PubMed 
involved_in visual perception IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoskeleton of presynaptic active zone IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in presynaptic active zone TAS
Traceable Author Statement
more info
 PubMed 
is_active_in presynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in presynaptic membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in presynaptic membrane NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
regulating synaptic membrane exocytosis protein 1
Names
RAB3-interacting protein 2
rab-3-interacting protein 2
rab3-interacting molecule 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016209.2 RefSeqGene

    Range
    5002..521597
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001168407.2 → NP_001161879.1  regulating synaptic membrane exocytosis protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001161879.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus and internal differences, compared to isoform 1.
    Source sequence(s)
    AK294868, AK295001, AL035633, AL445256, BC036608
    Consensus CDS
    CCDS55030.1
    UniProtKB/TrEMBL
    B7Z2W4
    Related
    ENSP00000385649.3, ENST00000401910.7
    Conserved Domains (3) summary
    cd04028
    Location:843 → 988
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  2. NM_001168408.2 → NP_001161880.1  regulating synaptic membrane exocytosis protein 1 isoform 3

    See identical proteins and their annotated locations for NP_001161880.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. The resulting isoform (3) has a shorter and distinct N-terminus and internal differences, compared to isoform 1.
    Source sequence(s)
    AK295001, AL035633, BC036608
    Consensus CDS
    CCDS55029.1
    UniProtKB/TrEMBL
    B7Z9Z3
    Related
    ENSP00000428328.1, ENST00000523963.5
    Conserved Domains (3) summary
    cd04028
    Location:648 → 793
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  3. NM_001168409.2 → NP_001161881.1  regulating synaptic membrane exocytosis protein 1 isoform 4

    See identical proteins and their annotated locations for NP_001161881.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. The resulting isoform (4) has a shorter and distinct N-terminus and internal differences, compared to isoform 1.
    Source sequence(s)
    AK295001, AK309185, AL035633, BC036608
    Consensus CDS
    CCDS55032.1
    UniProtKB/TrEMBL
    B7Z1R9
    Related
    ENSP00000411235.2, ENST00000425662.6
    Conserved Domains (3) summary
    cd04028
    Location:591 → 736
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:135 → 261
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:1 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  4. NM_001168410.2 → NP_001161882.1  regulating synaptic membrane exocytosis protein 1 isoform 5 precursor

    See identical proteins and their annotated locations for NP_001161882.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. The resulting isoform (5) has a shorter and distinct N-terminus and internal differences, compared to isoform 1.
    Source sequence(s)
    AK295001, AK296303, AK308658, AK316108, AL035633, BC036608
    Consensus CDS
    CCDS55031.1
    UniProtKB/TrEMBL
    B7Z9Z3
    Related
    ENSP00000428367.1, ENST00000517827.5
    Conserved Domains (3) summary
    cd04028
    Location:657 → 802
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:201 → 327
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:63 → 148
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  5. NM_001168411.2 → NP_001161883.1  regulating synaptic membrane exocytosis protein 1 isoform 6

    See identical proteins and their annotated locations for NP_001161883.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (6) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AK295001, AK300853, AL035633, BC036608, DB168720
    Consensus CDS
    CCDS55033.1
    UniProtKB/Swiss-Prot
    Q86UR5
    UniProtKB/TrEMBL
    Q3ZCW0
    Related
    ENSP00000402273.2, ENST00000414192.2
    Conserved Domains (1) summary
    cd04028
    Location:50 → 195
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

  6. NM_001350411.1 → NP_001337340.1  regulating synaptic membrane exocytosis protein 1 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AL034373, AL390056, AL590011

  7. NM_001350412.1 → NP_001337341.1  regulating synaptic membrane exocytosis protein 1 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AL390056, AL590011
    Conserved Domains (1) summary
    cl27627
    Location:54 → 132
    UPF0004; Uncharacterized protein family UPF0004

  8. NM_001350413.1 → NP_001337342.1  regulating synaptic membrane exocytosis protein 1 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AL034373, AL390056, AL590011
    Conserved Domains (1) summary
    cl27627
    Location:83 → 159
    UPF0004; Uncharacterized protein family UPF0004

  9. NM_001350414.2 → NP_001337343.1  regulating synaptic membrane exocytosis protein 1 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:830 → 975
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  10. NM_001350415.2 → NP_001337344.1  regulating synaptic membrane exocytosis protein 1 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:862 → 1007
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:426 → 633
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  11. NM_001350416.2 → NP_001337345.1  regulating synaptic membrane exocytosis protein 1 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:845 → 990
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  12. NM_001350417.2 → NP_001337346.1  regulating synaptic membrane exocytosis protein 1 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:672 → 817
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  13. NM_001350418.2 → NP_001337347.1  regulating synaptic membrane exocytosis protein 1 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:836 → 981
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  14. NM_001350419.2 → NP_001337348.1  regulating synaptic membrane exocytosis protein 1 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:596 → 741
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  15. NM_001350420.2 → NP_001337349.1  regulating synaptic membrane exocytosis protein 1 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:881 → 1026
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  16. NM_001350421.2 → NP_001337350.1  regulating synaptic membrane exocytosis protein 1 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:796 → 941
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:193 → 319
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:55 → 140
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  17. NM_001350422.2 → NP_001337351.1  regulating synaptic membrane exocytosis protein 1 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (4) summary
    cd04028
    Location:671 → 816
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25751
    Location:396 → 612
    DUF4045; Domain of unknown function (DUF4045)

  18. NM_001350423.2 → NP_001337352.1  regulating synaptic membrane exocytosis protein 1 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:759 → 904
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl28033
    Location:345 → 556
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  19. NM_001350424.2 → NP_001337353.1  regulating synaptic membrane exocytosis protein 1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:625 → 770
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:193 → 319
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:55 → 140
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  20. NM_001350425.2 → NP_001337354.1  regulating synaptic membrane exocytosis protein 1 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:829 → 974
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  21. NM_001350426.2 → NP_001337355.1  regulating synaptic membrane exocytosis protein 1 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (4) summary
    cd04028
    Location:621 → 766
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl28033
    Location:345 → 552
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  22. NM_001350427.2 → NP_001337356.1  regulating synaptic membrane exocytosis protein 1 isoform 23

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:647 → 792
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  23. NM_001350428.2 → NP_001337357.1  regulating synaptic membrane exocytosis protein 1 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:649 → 794
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:193 → 319
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:55 → 140
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  24. NM_001350429.2 → NP_001337358.1  regulating synaptic membrane exocytosis protein 1 isoform 25

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:769 → 914
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  25. NM_001350430.2 → NP_001337359.1  regulating synaptic membrane exocytosis protein 1 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (4) summary
    cd04028
    Location:648 → 793
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:193 → 319
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:55 → 140
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25751
    Location:373 → 589
    DUF4045; Domain of unknown function (DUF4045)

  26. NM_001350431.2 → NP_001337360.1  regulating synaptic membrane exocytosis protein 1 isoform 27

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:875 → 1020
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl28033
    Location:347 → 637
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  27. NM_001350432.2 → NP_001337361.1  regulating synaptic membrane exocytosis protein 1 isoform 28

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:617 → 762
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  28. NM_001350433.2 → NP_001337362.1  regulating synaptic membrane exocytosis protein 1 isoform 29

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:872 → 1017
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:345 → 615
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  29. NM_001350434.2 → NP_001337363.1  regulating synaptic membrane exocytosis protein 1 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:697 → 842
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  30. NM_001350435.2 → NP_001337364.1  regulating synaptic membrane exocytosis protein 1 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:826 → 971
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25836
    Location:391 → 569
    Retinal; Retinal protein

  31. NM_001350436.2 → NP_001337365.1  regulating synaptic membrane exocytosis protein 1 isoform 32

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:907 → 1052
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  32. NM_001350437.2 → NP_001337366.1  regulating synaptic membrane exocytosis protein 1 isoform 33

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:824 → 969
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:193 → 319
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:55 → 140
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15449
    Location:368 → 579
    Retinal; Retinal protein

  33. NM_001350438.2 → NP_001337367.1  regulating synaptic membrane exocytosis protein 1 isoform 34

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (5) summary
    cd04028
    Location:732 → 877
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:347 → 663
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15449
    Location:531 → 682
    Retinal; Retinal protein

  34. NM_001350439.2 → NP_001337368.1  regulating synaptic membrane exocytosis protein 1 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:820 → 965
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  35. NM_001350440.2 → NP_001337369.1  regulating synaptic membrane exocytosis protein 1 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (4) summary
    cd04028
    Location:620 → 765
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl28033
    Location:345 → 551
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  36. NM_001350441.2 → NP_001337370.1  regulating synaptic membrane exocytosis protein 1 isoform 37

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:819 → 964
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  37. NM_001350442.2 → NP_001337371.1  regulating synaptic membrane exocytosis protein 1 isoform 38

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (5) summary
    cd04028
    Location:733 → 878
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:347 → 664
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15449
    Location:532 → 683
    Retinal; Retinal protein

  38. NM_001350443.2 → NP_001337372.1  regulating synaptic membrane exocytosis protein 1 isoform 39

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:810 → 955
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  39. NM_001350444.2 → NP_001337373.1  regulating synaptic membrane exocytosis protein 1 isoform 40

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:768 → 913
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl28033
    Location:345 → 556
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  40. NM_001350445.2 → NP_001337374.1  regulating synaptic membrane exocytosis protein 1 isoform 41

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (4) summary
    cd04028
    Location:699 → 844
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:345 → 614
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  41. NM_001350446.2 → NP_001337375.1  regulating synaptic membrane exocytosis protein 1 isoform 42

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:905 → 1050
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:347 → 667
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  42. NM_001350447.2 → NP_001337376.1  regulating synaptic membrane exocytosis protein 1 isoform 43

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:792 → 937
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:345 → 580
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  43. NM_001350448.2 → NP_001337377.1  regulating synaptic membrane exocytosis protein 1 isoform 44

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:844 → 989
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  44. NM_001350449.2 → NP_001337378.1  regulating synaptic membrane exocytosis protein 1 isoform 45

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (4) summary
    cd04028
    Location:641 → 786
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25751
    Location:396 → 582
    DUF4045; Domain of unknown function (DUF4045)

  45. NM_001350450.2 → NP_001337379.1  regulating synaptic membrane exocytosis protein 1 isoform 46

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:624 → 769
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:193 → 319
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:55 → 140
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  46. NM_001350452.2 → NP_001337381.1  regulating synaptic membrane exocytosis protein 1 isoform 47

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    Conserved Domains (2) summary
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  47. NM_001350454.2 → NP_001337383.1  regulating synaptic membrane exocytosis protein 1 isoform 48

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:813 → 958
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25836
    Location:391 → 565
    Retinal; Retinal protein

  48. NM_001350455.2 → NP_001337384.1  regulating synaptic membrane exocytosis protein 1 isoform 49

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:597 → 742
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  49. NM_001350456.2 → NP_001337385.1  regulating synaptic membrane exocytosis protein 1 isoform 50

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:904 → 1049
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:347 → 666
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  50. NM_001350457.2 → NP_001337386.1  regulating synaptic membrane exocytosis protein 1 isoform 51

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:823 → 968
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  51. NM_001350458.2 → NP_001337387.1  regulating synaptic membrane exocytosis protein 1 isoform 52

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:846 → 991
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  52. NM_001350459.2 → NP_001337388.1  regulating synaptic membrane exocytosis protein 1 isoform 53

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:797 → 942
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:193 → 319
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:55 → 140
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  53. NM_001350460.2 → NP_001337389.1  regulating synaptic membrane exocytosis protein 1 isoform 54

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:803 → 948
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:345 → 574
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  54. NM_001350461.2 → NP_001337390.1  regulating synaptic membrane exocytosis protein 1 isoform 55

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:753 → 898
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:135 → 261
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:1 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  55. NM_001350462.2 → NP_001337391.1  regulating synaptic membrane exocytosis protein 1 isoform 56

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:858 → 1003
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:193 → 319
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:55 → 140
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  56. NM_001350463.2 → NP_001337392.1  regulating synaptic membrane exocytosis protein 1 isoform 57

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:738 → 883
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:135 → 261
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:1 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  57. NM_001350464.2 → NP_001337393.1  regulating synaptic membrane exocytosis protein 1 isoform 58

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    E5RGM0
    Related
    ENSP00000359448.4, ENST00000370420.8
    Conserved Domains (3) summary
    cd04028
    Location:739 → 884
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:135 → 261
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:1 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  58. NM_001350465.2 → NP_001337394.1  regulating synaptic membrane exocytosis protein 1 isoform 59

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z1R9
    Conserved Domains (3) summary
    cd04028
    Location:567 → 712
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:135 → 261
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:1 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  59. NM_001350466.2 → NP_001337395.1  regulating synaptic membrane exocytosis protein 1 isoform 60

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:740 → 885
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:135 → 261
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:1 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  60. NM_001350467.2 → NP_001337396.1  regulating synaptic membrane exocytosis protein 1 isoform 61

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    E5RGM0
    Conserved Domains (4) summary
    cd04028
    Location:712 → 857
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:135 → 261
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:264 → 500
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:1 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  61. NM_001350468.2 → NP_001337397.1  regulating synaptic membrane exocytosis protein 1 isoform 62

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    E5RGM0
    Related
    ENSP00000389503.2, ENST00000453976.6
    Conserved Domains (4) summary
    cd04028
    Location:687 → 832
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:135 → 261
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:1 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl28033
    Location:264 → 475
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  62. NM_001350469.2 → NP_001337398.1  regulating synaptic membrane exocytosis protein 1 isoform 63

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:763 → 908
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:135 → 261
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:1 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  63. NM_001350470.2 → NP_001337399.1  regulating synaptic membrane exocytosis protein 1 isoform 64 precursor

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:659 → 804
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:201 → 327
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:63 → 148
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  64. NM_001350471.2 → NP_001337400.1  regulating synaptic membrane exocytosis protein 1 isoform 65

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (4) summary
    cd04028
    Location:790 → 935
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:193 → 319
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:55 → 140
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25836
    Location:368 → 542
    Retinal; Retinal protein

  65. NM_001350472.2 → NP_001337401.1  regulating synaptic membrane exocytosis protein 1 isoform 66 precursor

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:632 → 777
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:201 → 327
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:63 → 148
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  66. NM_001350473.2 → NP_001337402.1  regulating synaptic membrane exocytosis protein 1 isoform 67 precursor

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z9Z3
    Conserved Domains (3) summary
    cd04028
    Location:633 → 778
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:201 → 327
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:63 → 148
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  67. NM_001350474.2 → NP_001337403.1  regulating synaptic membrane exocytosis protein 1 isoform 68 precursor

    Status: REVIEWED

    Source sequence(s)
    AL035633, AL445256, AL590011
    UniProtKB/TrEMBL
    B7Z2W4
    Related
    ENSP00000430359.1, ENST00000517433.5
    Conserved Domains (3) summary
    cd04028
    Location:754 → 899
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:201 → 327
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:63 → 148
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  68. NM_014989.7 → NP_055804.2  regulating synaptic membrane exocytosis protein 1 isoform 1

    See identical proteins and their annotated locations for NP_055804.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AL034373, AL035633, AL390056, AL445256, AL590011
    Consensus CDS
    CCDS47449.1
    UniProtKB/Swiss-Prot
    A7MBN6, B7Z2M0, B7Z2Q9, B7Z3S3, B7Z6S2, E7EX08, E9PCB7, E9PCZ1, E9PF48, E9PHF5, E9PHR1, O15048, Q5JY21, Q5JY25, Q5SZK1, Q86UR5, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6
    Related
    ENSP00000428417.1, ENST00000521978.6
    Conserved Domains (6) summary
    cd04028
    Location:1523 → 1668
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:742 → 868
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:604 → 689
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam04642
    Location:191 → 284
    DUF601; Protein of unknown function, DUF601
    cl25574
    Location:257 → 536
    TOP2c; TopoisomeraseII
    cl28890
    Location:131 → 186
    FYVE_like_SF; FYVE domain like superfamily

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    71886550..72403145
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017010517.3 → XP_016866006.1  regulating synaptic membrane exocytosis protein 1 isoform X4

  2. XM_047418419.1 → XP_047274375.1  regulating synaptic membrane exocytosis protein 1 isoform X10

  3. XM_017010522.3 → XP_016866011.1  regulating synaptic membrane exocytosis protein 1 isoform X22

    Related
    ENSP00000513179.1, ENST00000697193.1
    Conserved Domains (6) summary
    cd04028
    Location:1370 → 1515
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:742 → 868
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PLN03237
    Location:257 → 536
    PLN03237; DNA topoisomerase 2; Provisional
    cd00992
    Location:604 → 689
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam04642
    Location:191 → 284
    DUF601; Protein of unknown function, DUF601
    cl28890
    Location:131 → 186
    FYVE_like_SF; FYVE domain like superfamily

  4. XM_017010520.3 → XP_016866009.1  regulating synaptic membrane exocytosis protein 1 isoform X6

  5. XM_017010516.3 → XP_016866005.1  regulating synaptic membrane exocytosis protein 1 isoform X2

  6. XM_017010519.3 → XP_016866008.1  regulating synaptic membrane exocytosis protein 1 isoform X21

  7. XM_017010521.3 → XP_016866010.1  regulating synaptic membrane exocytosis protein 1 isoform X7

  8. XM_017010525.3 → XP_016866014.1  regulating synaptic membrane exocytosis protein 1 isoform X24

  9. XM_024446369.2 → XP_024302137.1  regulating synaptic membrane exocytosis protein 1 isoform X1

    Conserved Domains (7) summary
    cd04028
    Location:1481 → 1626
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:742 → 868
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:604 → 689
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam04642
    Location:191 → 284
    DUF601; Protein of unknown function, DUF601
    cl25574
    Location:257 → 536
    TOP2c; TopoisomeraseII
    cl28033
    Location:873 → 1189
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
    cl28890
    Location:131 → 186
    FYVE_like_SF; FYVE domain like superfamily

  10. XM_017010518.3 → XP_016866007.1  regulating synaptic membrane exocytosis protein 1 isoform X5

  11. XM_011535604.4 → XP_011533906.2  regulating synaptic membrane exocytosis protein 1 isoform X23

  12. XM_047418421.1 → XP_047274377.1  regulating synaptic membrane exocytosis protein 1 isoform X25

    Related
    ENSP00000429959.1, ENST00000517960.5

  13. XM_047418416.1 → XP_047274372.1  regulating synaptic membrane exocytosis protein 1 isoform X3

  14. XM_047418417.1 → XP_047274373.1  regulating synaptic membrane exocytosis protein 1 isoform X8

  15. XM_047418418.1 → XP_047274374.1  regulating synaptic membrane exocytosis protein 1 isoform X9

  16. XM_047418423.1 → XP_047274379.1  regulating synaptic membrane exocytosis protein 1 isoform X13

  17. XM_047418420.1 → XP_047274376.1  regulating synaptic membrane exocytosis protein 1 isoform X11

  18. XM_047418424.1 → XP_047274380.1  regulating synaptic membrane exocytosis protein 1 isoform X14

  19. XM_047418426.1 → XP_047274382.1  regulating synaptic membrane exocytosis protein 1 isoform X16

    Related
    ENSP00000430502.1, ENST00000520567.5

  20. XM_047418422.1 → XP_047274378.1  regulating synaptic membrane exocytosis protein 1 isoform X12

  21. XM_047418425.1 → XP_047274381.1  regulating synaptic membrane exocytosis protein 1 isoform X15

  22. XM_017010537.3 → XP_016866026.1  regulating synaptic membrane exocytosis protein 1 isoform X17

    UniProtKB/TrEMBL
    B7Z2W4

  23. XM_017010546.3 → XP_016866035.1  regulating synaptic membrane exocytosis protein 1 isoform X20

    UniProtKB/TrEMBL
    B7Z2W4

  24. XM_024446372.2 → XP_024302140.1  regulating synaptic membrane exocytosis protein 1 isoform X18

    UniProtKB/TrEMBL
    B7Z2W4
    Conserved Domains (3) summary
    cd04028
    Location:870 → 1015
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:216 → 342
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:78 → 163
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  25. XM_017010544.3 → XP_016866033.1  regulating synaptic membrane exocytosis protein 1 isoform X19

    UniProtKB/TrEMBL
    B7Z2W4

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    73067717..73580721
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054354732.1 → XP_054210707.1  regulating synaptic membrane exocytosis protein 1 isoform X4

  2. XM_054354738.1 → XP_054210713.1  regulating synaptic membrane exocytosis protein 1 isoform X10

  3. XM_054354734.1 → XP_054210709.1  regulating synaptic membrane exocytosis protein 1 isoform X6

  4. XM_054354730.1 → XP_054210705.1  regulating synaptic membrane exocytosis protein 1 isoform X2

  5. XM_054354735.1 → XP_054210710.1  regulating synaptic membrane exocytosis protein 1 isoform X7

  6. XM_054354729.1 → XP_054210704.1  regulating synaptic membrane exocytosis protein 1 isoform X1

  7. XM_054354733.1 → XP_054210708.1  regulating synaptic membrane exocytosis protein 1 isoform X5

  8. XM_054354731.1 → XP_054210706.1  regulating synaptic membrane exocytosis protein 1 isoform X3

  9. XM_054354736.1 → XP_054210711.1  regulating synaptic membrane exocytosis protein 1 isoform X8

  10. XM_054354737.1 → XP_054210712.1  regulating synaptic membrane exocytosis protein 1 isoform X9

  11. XM_054354742.1 → XP_054210717.1  regulating synaptic membrane exocytosis protein 1 isoform X13

  12. XM_054354740.1 → XP_054210715.1  regulating synaptic membrane exocytosis protein 1 isoform X26

  13. XM_054354743.1 → XP_054210718.1  regulating synaptic membrane exocytosis protein 1 isoform X27

  14. XM_054354746.1 → XP_054210721.1  regulating synaptic membrane exocytosis protein 1 isoform X28

  15. XM_054354739.1 → XP_054210714.1  regulating synaptic membrane exocytosis protein 1 isoform X11

  16. XM_054354744.1 → XP_054210719.1  regulating synaptic membrane exocytosis protein 1 isoform X14

  17. XM_054354747.1 → XP_054210722.1  regulating synaptic membrane exocytosis protein 1 isoform X16

  18. XM_054354741.1 → XP_054210716.1  regulating synaptic membrane exocytosis protein 1 isoform X12

  19. XM_054354745.1 → XP_054210720.1  regulating synaptic membrane exocytosis protein 1 isoform X15

  20. XM_054354748.1 → XP_054210723.1  regulating synaptic membrane exocytosis protein 1 isoform X17

  21. XM_054354751.1 → XP_054210726.1  regulating synaptic membrane exocytosis protein 1 isoform X20

  22. XM_054354749.1 → XP_054210724.1  regulating synaptic membrane exocytosis protein 1 isoform X18

  23. XM_054354750.1 → XP_054210725.1  regulating synaptic membrane exocytosis protein 1 isoform X19

  24. XM_054354753.1 → XP_054210728.1  regulating synaptic membrane exocytosis protein 1 isoform X30

  25. XM_054354752.1 → XP_054210727.1  regulating synaptic membrane exocytosis protein 1 isoform X29

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q86UR5.1 GenPept UniProtKB/Swiss-Prot:Q86UR5

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