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Zfp160 zinc finger protein 160 [ Mus musculus (house mouse) ]

Gene ID: 224585, updated on 28-Oct-2024

Summary

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Official Symbol
Zfp160provided by MGI
Official Full Name
zinc finger protein 160provided by MGI
Primary source
MGI:MGI:108187
See related
Ensembl:ENSMUSG00000067942 AllianceGenome:MGI:108187
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
F11; HZF5; KR18; HKr18; mszf47; mKIAA1611; 6720480D16Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in central nervous system; early conceptus; foregut; inner cell mass; and oocyte. Orthologous to several human genes including ZNF665 (zinc finger protein 665). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Broad expression in CNS E18 (RPKM 6.3), CNS E14 (RPKM 6.3) and 20 other tissues See more
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Genomic context

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See Zfp160 in Genome Data Viewer
Location:
17 A3.2; 17 11.4 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (21229203..21249119)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (21008941..21028857)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor, pseudogene 145 Neighboring gene STARR-seq mESC enhancer starr_42003 Neighboring gene vomeronasal 1 receptor 233 Neighboring gene STARR-positive B cell enhancer ABC_E7493 Neighboring gene myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog pseudogene Neighboring gene predicted gene 5681

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of differentially expressed genes in mouse spermatogenesis. Pang AL, et al. J Androl, 2003 Nov-Dec. PMID 14581517
  2. Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. Agata Y, et al. Gene, 1998 Jun 15. PMID 9630514
  3. Detailed comparative map of human chromosome 19q and related regions of the mouse genome. Stubbs L, et al. Genomics, 1996 Aug 1. PMID 8812484
  4. Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction. Millien G, et al. Gene Expr Patterns, 2008 Jan. PMID 18023262, Free PMC Article
  5. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 160

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145483.2 → NP_663458.2  zinc finger protein 160

    Status: VALIDATED

    Source sequence(s)
    AK078453, AK143313, AK161712, BE989157
    Consensus CDS
    CCDS28434.1
    UniProtKB/TrEMBL
    E9Q459
    Related
    ENSMUSP00000086191.6, ENSMUST00000088811.7
    Conserved Domains (6) summary
    smart00349
    Location:8 → 68
    KRAB; krueppel associated box
    COG5048
    Location:200 → 635
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:512 → 532
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:202 → 224
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:8 → 47
    KRAB; KRAB box
    pfam13465
    Location:216 → 240
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    21229203..21249119
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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