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Tsx testis specific X-linked gene [ Mus musculus (house mouse) ]

Gene ID: 22127, updated on 6-Jun-2024

Summary

Official Symbol
Tsxprovided by MGI
Official Full Name
testis specific X-linked geneprovided by MGI
Primary source
MGI:MGI:108118
See related
Ensembl:ENSMUSG00000031329 AllianceGenome:MGI:108118
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Acts upstream of or within adult behavior; fertilization; and male gonad development. Located in cytoplasm and nucleus. Is expressed in Sertoli cell. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 4.8), limb E14.5 (RPKM 0.4) and 5 other tissues See more
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Genomic context

See Tsx in Genome Data Viewer
Location:
X D; X 46.12 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (102452618..102468194)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (103409012..103424588)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_47688 Neighboring gene caudal type homeobox 4 Neighboring gene predicted gene 9516 Neighboring gene cysteine-rich hydrophobic domain 1 Neighboring gene STARR-seq mESC enhancer starr_47691 Neighboring gene origin of replication in Tsix Neighboring gene X (inactive)-specific transcript, opposite strand Neighboring gene origin of replication in exon 1 of Xist Neighboring gene inactive X specific transcripts Neighboring gene predicted gene 14861

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within adult behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within fertilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within male gonad development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in male germ cell nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
testis-specific protein TSX
Names
testis-specific X-linked protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001410244.1NP_001397173.1  testis-specific protein TSX

    Status: VALIDATED

    Source sequence(s)
    AL669964
    UniProtKB/Swiss-Prot
    P70675
    UniProtKB/TrEMBL
    F8SHA8, F8SHC2, F8SHC6, F8SHE1, Q78Z65
  2. NM_009440.3NP_033466.1  testis-specific protein TSX

    See identical proteins and their annotated locations for NP_033466.1

    Status: VALIDATED

    Source sequence(s)
    AV265136, BC048493
    Consensus CDS
    CCDS41090.1
    UniProtKB/Swiss-Prot
    P70675
    UniProtKB/TrEMBL
    F8SHA8, F8SHC2, F8SHC6, F8SHE1, Q78Z65
    Related
    ENSMUSP00000033691.5, ENSMUST00000033691.5
    Conserved Domains (1) summary
    pfam17397
    Location:1144
    DUF5404; Family of unknown function (DUF5404)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    102452618..102468194
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527941.2XP_006528004.1  testis-specific protein TSX isoform X1

    See identical proteins and their annotated locations for XP_006528004.1

    UniProtKB/Swiss-Prot
    P70675
    UniProtKB/TrEMBL
    F8SHA8, F8SHC2, F8SHC6, F8SHE1, Q78Z65
    Conserved Domains (1) summary
    pfam17397
    Location:1144
    DUF5404; Family of unknown function (DUF5404)
  2. XM_006527940.4XP_006528003.1  testis-specific protein TSX isoform X1

    See identical proteins and their annotated locations for XP_006528003.1

    UniProtKB/Swiss-Prot
    P70675
    UniProtKB/TrEMBL
    F8SHA8, F8SHC2, F8SHC6, F8SHE1, Q78Z65
    Conserved Domains (1) summary
    pfam17397
    Location:1144
    DUF5404; Family of unknown function (DUF5404)